1057675-92-9Relevant academic research and scientific papers
The total synthesis and biological evaluation of nafuredin-γ and its analogues
Nagamitsu, Tohru,Takano, Daisuke,Seki, Miyuki,Arima, Shiho,Ohtawa, Masaki,Shiomi, Kazuro,Harigaya, Yoshihiro,Omura, Satoshi
, p. 8117 - 8127 (2008)
Nafuredin (1) is converted to nafuredin-γ (2) under mild basic conditions and both compounds exhibit the same inhibitory activity and selectivity against NADH-fumarate reductase (complex I). The total synthesis of 2 was achieved by a convergent approach u
