1057682-03-7 Usage
General Description
(S)-6-(3-Methylpiperazin-1-yl)nicotinonitrile, also known as SCH 23390, is a chemical compound that acts as a selective D1 receptor antagonist. It is commonly used in research to study the effects of dopamine receptors in the brain and has been found to have potential therapeutic applications in the treatment of various neurological and psychiatric disorders. The compound is a potent and specific antagonist of the D1 dopamine receptor, which plays a crucial role in modulating various physiological and behavioral functions. This chemical has been studied for its potential role in treating conditions such as schizophrenia, Parkinson's disease, and drug addiction. Its unique structure and pharmacological activity make it a valuable tool for investigating the role of dopamine receptors in the central nervous system.
Check Digit Verification of cas no
The CAS Registry Mumber 1057682-03-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,5,7,6,8 and 2 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1057682-03:
(9*1)+(8*0)+(7*5)+(6*7)+(5*6)+(4*8)+(3*2)+(2*0)+(1*3)=157
157 % 10 = 7
So 1057682-03-7 is a valid CAS Registry Number.
1057682-03-7Relevant articles and documents
POLY-ADP RIBOSE POLYMERASE (PARP) INHIBITORS
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Page/Page column 110; 113, (2018/07/29)
The present invention is related to a pharmaceutical composition comprising a pharmaceutically acceptable carrier or diluent and a compound represented by the following structural formula: The present invention is also related a method of treating a subject with a disease which can be ameliorated by inhibition of poly(ADP-ribose)polymerase (PARP). The definitions of the variables are provided herein.
ORGANIC COMPOUNDS AND THEIR USES
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Page/Page column 34, (2008/12/07)
The present disclosure relates to compounds relating to the diagnosis and treatment of pathologies relating to the Hedgehog pathway, including but not limited to tumor formation, cancer, neoplasia, and non-malignant hyperproliferative disorders; specifically relating to compounds of formula (I).
