105785-70-4Relevant articles and documents
Quinoline compounds as antiallergic and antiinflammatory agents
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, (2008/06/13)
There are disclosed compounds of the formula STR1 wherein R1 is STR2 n is 0-5; R2 is hydrogen, loweralkyl, loweralkoxy, lower alkoxycarbonyl, trifluoromethyl, nitro, cyano or halo; R3 is hydrogen or loweralkyl; R4 hydrogen, lower alkyl, --COOR3 or STR3 R5 is lower alkyl, monofluoroloweralkyl, difluoroloweralkyl, polyfluoroloweralkyl, perfluoroloweralkyl or STR4 and the pharmaceutically acceptable salts thereof, and their use in the treatment of leukotriene-mediated naso-bronchial obstructive airpassageway conditions, such as allergic rhinitis, allergic bronchial asthma and the like, and as antiinflammatory agents.
2-(phenoxymethyl)-quinazolines as antiallergic and antiinflammatory agents
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, (2008/06/13)
There are disclosed compounds of the formula STR1 wherein STR2 R2 is hydrogen, loweralkyl, loweralkoxy, lower alkoxycarbonyl, trifluoromethyl, nitro, cyano or halo; R3 is hydrogen or loweralkyl; R4 is hydrogen, lower alkyl, --COOR3 or STR3 R5 is lower alkyl, monofluoroloweralkyl, difluoroloweralkyl, polyfluoroloweralkyl, perfluoroloweralkyl or STR4 and the pharmaceutically acceptable salts thereof, and their use in the treatment of leukotriene-mediated naso-bronchial obstructive airpassageway conditions, such as allergic rhinitis, allergic bronchial asthma and the like, and as antiinflammatory agents.