10579-62-1

Usage

Uses

Used in Pharmaceutical Industry:
2,2-dichloro-1-(3,4-dihydroisoquinolin-2(1H)-yl)ethanone is used as a synthetic intermediate for the production of various pharmaceuticals. Its unique structure and reactivity contribute to the development of new drugs with potential therapeutic applications.
Used in Organic Chemistry:
In the field of organic chemistry, 2,2-dichloro-1-(3,4-dihydroisoquinolin-2(1H)-yl)ethanone serves as a key intermediate in the synthesis of complex organic compounds. Its presence of chlorine atoms allows for further functionalization and modification of the molecule, facilitating the creation of a wide range of chemical entities.
Safety Considerations:
Given its reactivity and potential hazards, 2,2-dichloro-1-(3,4-dihydroisoquinolin-2(1H)-yl)ethanone must be handled and stored with care. Adherence to proper safety protocols is essential to mitigate any health or environmental risks associated with 2,2-dichloro-1-(3,4-dihydroisoquinolin-2(1H)-yl)ethanone.

Upstream product

• 79-43-6 dichloro-acetic acid 
• 56971-73-4 N-methylene-2-phenethylamine 
• 91-21-4 1,2,3,4-tetrahydroisoquinoline 
• 64-04-0 phenethylamine 
• 79-36-7 dichloroacethyl chloride 
• 50-00-0 formaldehyd 
• 39106-18-8 2,2-dichloro-N-(2-phenylethyl)acetamide 

Relevant academic research and scientific papers

Reaction of polychloroacetamides with amines: Reductive dechlorination and aziridine formation

Treatment of trichloroacetamides with amines undergoes reductive dechlorination via single-electron transfer process to afford dichloroacetamides in good yields. Reaction of trichloro- and dichloroacetamides with DBU provides a new synthetic method of azi

Improved methods for the synthesis of N-acyltetrahydroisoquinolines

One-pot procedures for the synthesis of N-acyltetrahydroisoquinolines have been developed from 2-phenylethylamines, acyl chlorides or carboxylic acids and aldehydes.

Haloacyl 1-substituted-1,2,3,4-tetrahydro-isoquinolines as herbicide antidotes

Haloacyl 1-substituted-1,2,3,4-tetrahydroisoquinoline compounds are antidotes for thiocarbamate, triazine-type and acetamide herbicides. These antidote compounds are especially effective in safening acetamide herbicides used to control grassy and broadlea

The use of N-dichloroacetyl-1,2,3,4-tetrahydroisoquinolin as antidote for the protection of cultivated plants against damage caused by herbicidally active acetanilides; combinations thus obtained and process for their preparation

The known N-dichloroacetyl-1,2,3,4-tetrahydroisoquinoline of the formula , R represents an optionally substituted N-containing heterocyclic radical,, X and Y are identical or different and represent alkyl,, Z represents halogen, and, , n represents 0, 1 or 2,and their herbicidally active acid addition salts and metal salt complexes, - or of the formula , R1 represents alkyl, halogen, haloalkyl, alkylthio, alkylsulphonyl, aminosulphonyl, cyano or nitro,, R2 and R3 are identical or different and represent hydrogen, alkyl, halogen, haloalkyl or optionally substituted phenyl,, R4 represents alkyl or optionally substituted phenyl, and, , m represents integers from 0 to 5,or of the formula , A represents oxygen, sulphur or the group , R7 represents hydrogen or alkyl,, R8 represents hydrogen, alkyl, haloalkyl, alkenyl, alkynyl, cycloalkyl, halogen, optionally substituted aryl and aralkyl or the groups -OR11, -SR11 and NR10R11,, R10 represents hydrogen, alkyl or optionally substituted aryl,, R11 represents hydrogen, alkyl, haloalkyl, alkenyl, alkynyl, cycloalkyl or optionally substituted aralkyl,, R5 represents alkyl,, R6 represents alkyl or halogen,, R9 represents halogen, and, , p represents the numbers 0, 1 or 2.