105827-63-2 Usage
Structure
Cyclohexadiene ring with a carboxylic acid group at position 1 and two methyl groups at positions 2 and 4
Functional groups
Carboxylic acid, cyclohexadiene, and methyl groups
Applications
a. Organic synthesis
b. Building block for pharmaceuticals and agrochemicals
c. Production of flavors and fragrances
Chemical properties
Versatile and valuable in organic chemistry
Hazards
Potential hazards and toxicological properties; should be handled with care
Reactivity
Not specified in the material provided, but it is a carboxylic acid, which generally reacts with bases, metals, and other nucleophiles
Stability
Not specified in the material provided, but it is a carboxylic acid, which is generally stable under normal conditions
Storage
Not specified in the material provided, but it should be stored in a cool, dry place, away from incompatible substances, and in a sealed container to prevent degradation or reactions with moisture or air
Safety precautions
Use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats when handling 1,3-Cyclohexadiene-1-carboxylicacid,2,4-dimethyl-(9CI); follow proper disposal procedures and handle according to the material safety data sheet (MSDS) guidelines
Check Digit Verification of cas no
The CAS Registry Mumber 105827-63-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,8,2 and 7 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 105827-63:
(8*1)+(7*0)+(6*5)+(5*8)+(4*2)+(3*7)+(2*6)+(1*3)=122
122 % 10 = 2
So 105827-63-2 is a valid CAS Registry Number.
105827-63-2Relevant articles and documents
SYNTHETIC STUDIES ON NOGALAMYCIN CONGENERS ; TOTAL SYNTHESES OF (+)-NOGARENE, (+)-7-DEOXYNOGAROL, AND (+)-7-CON-O-METHYLNOGAROL
Kawasaki, Motoji,Matsuda, Fuyuhiko,Terashima, Shiro
, p. 5727 - 5744 (2007/10/02)
According to the retrosynthetic perspective, the title total syntheses were accomplished by employing the regioselective Diels-Alder reactions of the (+)-naphthoquinone (5), the CDEF-ring system of nogalamycin congeners, with various structural types of dienes (8, 16, and 26).The highly functionalized dienes (16 and 26) incorporating all the functionalities present in the A-rings of (+)-7-deoxynogarol (3) and (+)-7-con-O-methylnogarol (2), were prepared efficiently by way of the 1,4-cyclohexadiene and 2-cyclohexanone derivatives (6 and 21), respectively.Reaction mechanism of the key Diels-Alder reaction was also discussed in terms of its stereoselectivity.
