1058719-33-7Relevant academic research and scientific papers
Synthesis of 4-oxo-4,7-dihydrofuro[2,3-b]pyridine-5-carboxamides with broad-spectrum human herpesvirus polymerase inhibition
Schnute, Mark E.,Brideau, Roger J.,Collier, Sarah A.,Cudahy, Michele M.,Hopkins, Todd A.,Knechtel, Mary L.,Oien, Nancee L.,Sackett, Robert S.,Scott, Allen,Stephan, Mari L.,Wathen, Michael W.,Wieber, Janet L.
scheme or table, p. 3856 - 3859 (2009/04/06)
A versatile synthesis of 4-oxo-4,7-dihydrofuro[2,3-b]pyridine-5-carboxylate esters has been developed which has lead to the identification of a new series of non-nucleoside inhibitors of human herpesvirus polymerases HCMV, HSV-1, EBV, and VZV with high specificity compared to human DNA polymerases.
