1058744-75-4Relevant academic research and scientific papers
Pyrrolidine-pyridine base catalysts for the enantioselective Michael addition of ketones to chalcones
Xu, Da-Zhen,Shi, Sen,Liu, Yingjun,Wang, Yongmei
, p. 9344 - 9349 (2009)
A series of pyrrolidine-pyridine base organocatalysts have been developed and 3a found to be a highly effective catalyst for the asymmetric Michael addition reactions of ketones to chalcones. The reaction generated the corresponding products 1, 5-diketone
Direct asymmetric michael additions of ketones to nitroolefins and chalcones catalyzed by a Chiral C2-symmetric pyrrolidine-based tetraamine
Ma, Shijun,Wu, Lulu,Liu, Ming,Wang, Yongmei
, p. 2707 - 2713 (2013/01/15)
C2-Symmetric pyrrolidine-based tetraamine, available from commercially starting materials, showed good catalytic activity for asymmetric Michael additions of ketones to nitroalkenes especially to chalcones. The reactions proceeded to give the corresponding products in good yields and in a highly selective manner.
