105877-20-1Relevant academic research and scientific papers
Platinum complexes from pyridine-imine ligands with pendent functional groups
Abo-Amer, Anwar,Boyle, Paul D.,Puddephatt, Richard J.
, (2021)
Notable differences are observed in reactions of platinum(II) precursor complexes with pyridine-imine ligands of formula 2-C5H4NCH = NCH2-C6H4OR with R = Me or H. The ligand 2-C5H4NCH = N-2-C6H4OMe, L1, gave simple complexes [PtXY(L1)], XY = Me,Me; Me,Cl; Cl,Cl. However, the ligand 2-C5H4NCH = NCH2-2-C6H4OH, L2, gave either [PtCl(κ3-N,N,O-2-C5H4NCH2N = CH-2-C6H4O)], in which the ligand L2 had undergone a proton migration and a deprotonation, or a more complex product arising from reaction with solvent. The ligand 2-C5H4NCH = NCH2-4-C6H4OH, L3, gave a complex [PtCl2(L3)], which formed a polymer in the solid state through intermolecular OH.Cl hydrogen bonding.
COMPLEXATION D'IMINOPYRIDINES PAR LE SEL DE ZEISE: VOIE D'ACCES A DES CONJUGUES ESTRADIOL-cis-DICHLORO PLATINE. ETUDE STRUCTURALE DU COMPLEXE cis-PtCl2,H20
Pointeau, Philippe,Patin, Henri,Mousser, Abdelhamid,Marouille, Jean-Yves Le
, p. 263 - 276 (2007/10/02)
In order to synthesize penta- and hexa-gonal platinum(II) metallocycles, bidentate ligands such as iminopyridines (L) have been prepared and characterized.The (2-pyridil)CH=NR1 and (2-pyridil)CH2N=CR1R2 ligands react with Zeise's salt to afford directly the pentagonal chelates PtCl2L.Their structure and the cis-stereochemistry were shown by the usual spectroscopic methods and for cis-PtCl2,H2O by an X-ray diffraction study.On the other hand, the (2-pyridil)(CH2)2N=CR1R2 ligands do not afford the expected hexagonal metallocycles; instead, after complexation at the nitrogen atom of the imine they give rise to the (2-pyridil)ethylamine complex formed after hydrolysis of the coordinated ligands.Complexes trans-1R2>-PtCl2 represent when R1 is estradiol a model for "cytotoxic with delayed activity".
