105906-46-5Relevant academic research and scientific papers
One-Pot Transfer Hydrogenation Reductive Amination of Aldehydes and Ketones by Iridium Complexes “on Water”
Ouyang, Lu,Xia, Yanping,Liao, Jianhua,Luo, Renshi
, p. 6387 - 6391 (2020/09/11)
An efficient and practical one-pot transfer hydrogenation reductive amination of aldehydes and ketones with amines has been developed by using iridium complexes as catalysts and formic acid as hydrogen source in aqueous solution, providing an environmentally friendly methodology for the construction of a wide range of functionalized amine compounds in excellent yields (≈ 80 %-95 %). This effective methodology can be scaled up to gram scale with 0.1 mol-% catalyst loading and also be employed in the synthesis of medical substances such as Meclizine.
1,2,3-Triazole-boranes: Stable and efficient reagents for ketone and aldehyde reductive amination in organic solvents or in water
Liao, Wenyan,Chen, Yunfeng,Liu, Yuxiu,Duan, Haifeng,Petersen, Jeffrey L.,Shi, Xiaodong
supporting information; experimental part, p. 6436 - 6438 (2010/03/04)
Air, moisture and thermally stable 1,2,3-triazole-borane complexes were developed as new practical reagents for ketone/aldehyde amination with high efficiency and excellent substrate diversity.
