1059192-57-2Relevant academic research and scientific papers
Conformationally constrained adamantaneoxazolines of pharmacological interest
Papanastasiou, Ioannis,Foscolos, George B.,Tsotinis, Andrew,Olah, Judit,Ovadi, Judit,Radhika Prathalingam,Kelly, John M.
, p. 2043 - 2061 (2008)
New conformationally constrained adamantane 2-oxazoline building blocks 1-4 were synthesized and their antimicrotubule and antitrypanosomal potency was investigated. Although most of the new compounds affect tubulin polymerization, this does not make a major contribution to trypanocidal activity.
