105931-88-2 Usage
General Description
1,3,4,5-Tetrahydro-5-acetyl-4-phenyl-1-(phenylmethyl)-2H-1,5-benzodiazepin-2-one, also known as tetrazepam, is a benzodiazepine derivative with sedative and muscle relaxant properties. It works by enhancing the inhibitory effects of gamma-aminobutyric acid (GABA), a neurotransmitter in the central nervous system, leading to a decrease in neuronal excitability. Tetrazepam is commonly used to treat muscle spasticity and spasm, as well as anxiety and tension. However, it has been associated with rare cases of severe liver injury, and its use should be closely monitored and limited to cases where other treatments have been ineffective.
Check Digit Verification of cas no
The CAS Registry Mumber 105931-88-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,9,3 and 1 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 105931-88:
(8*1)+(7*0)+(6*5)+(5*9)+(4*3)+(3*1)+(2*8)+(1*8)=122
122 % 10 = 2
So 105931-88-2 is a valid CAS Registry Number.
InChI:InChI=1/C24H22N2O2/c1-18(27)26-22-15-9-8-14-21(22)25(17-19-10-4-2-5-11-19)24(28)16-23(26)20-12-6-3-7-13-20/h2-15,23H,16-17H2,1H3
105931-88-2Relevant articles and documents
SYNTHESIS AND DYNAMIC STEREOCHEMISTRY OF 1,5-DISUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-1,5-BENZODIAZEPIN-2-ONES
Puodzhyunaite, B. A.,Yanchene, R. A.,Stumbryavichyute, Z. A.,Mikul'skis, P. P.
, p. 206 - 210 (1986)
The 1-isopropyl and 1-benzyl derivatives of 1,5-tetrahydrobenzodiazepin-2-one were synthesized by alkylation under the conditions of phase-transfer catalysis.The inversion of the heterocycle was studied by PMR spectroscopy, and the free energies of activa