105938-38-3Relevant academic research and scientific papers
Improvement of the water solubility of tolfenamic acid by new multiple-component crystals produced by mechanochemical methods
Gaglioti,Chierotti,Grifasi,Gobetto,Griesser,Hasa,Voinovich
, p. 8252 - 8262 (2014)
Tolfenamic acid (HTA) is a drug characterized by very poor water solubility (13.6 nM under acidic conditions) and moderate solubility in ethanol (0.17 M). A series of new multicomponent crystals have been obtained by applying mechanochemical methods (i.e.
