1059604-40-8Relevant academic research and scientific papers
Synthesis of new thiazolo[3,2-a]pyrimidin-5-one derivatives in reaction of 3-allyl-2-thiouracils cyclization
Studzinska, Renata,Wroblewski, Marcin,Draminski, Marcin
experimental part, p. 1953 - 1961 (2009/04/06)
The series of thiazolo[3,2-a]pyrimidin-5-one derivatives in cyclization reaction of 3-allyl-2-thiouracil derivatives with iodine monochloride, and then hydrogen iodide elimination from intermediate reaction product has been obtained. On the basis of the studies of reaction kinetics, the elimination reaction mechanism has been proposed. Moreover, the influence of substituent on the reaction elimination rate has been investigated.
