1059629-67-2Relevant academic research and scientific papers
Synthesis of pyrazino[1,2-a]benzimidazol-1(2H)ones via a microwave assisted Buchwald-Hartwig type reaction
Alen, Jo,Robeyns, Koen,De Borggraeve, Wim M.,Van Meervelt, Luc,Compernolle, Frans
, p. 8128 - 8133 (2008/12/21)
A convenient synthesis of substituted pyrazino[1,2-a]benzimidazol-1(2H)ones starting from 3,5-dichloropyrazinones has been accomplished. Various 3-anilino-pyrazinones were easily converted to the desired tricyclic structures by applying a microwave assisted Buchwald-Hartwig type cyclization.
