1059685-89-0Relevant academic research and scientific papers
Synthesis and anti-inflammatory activity of 2-(2-aroylaroxy)-4,6-dimethoxy pyrimidines
Venu,Khanum,Firdouse, Aiysha,Manuprasad,Shashikanth, Sheena,Mohamed, Riyaz,Vishwanth, Bannikuppe Sannanaik
scheme or table, p. 4409 - 4412 (2009/04/06)
Abstract-Reaction of 6a-f individually with 2-methylsulfonyl-4,6-dimethoxypyrimidine yielded 7a-f in excellent yield. The newly synthesized heterocycles were characterized by IR, 1H NMR, and mass spectral data. Compounds 7a-f was screened for their anti-inflammatory activity and were compared with standard drugs. Of the compounds studied, the compound 7e showed more potent activity than the standard drugs at all doses tested.
