10597-55-4 Usage
Uses
Used in Pharmaceutical Industry:
1H-Benzimidazol-4-amine,6-chloro-(9CI) is used as a histamine H3 receptor antagonist for its potential role in treating various conditions related to histamine receptor activity. Its ability to modulate histamine signaling pathways makes it a promising candidate for the development of new drugs targeting histamine-related disorders.
Used in Anti-inflammatory Applications:
1H-Benzimidazol-4-amine,6-chloro-(9CI) is used as an anti-inflammatory agent for its potential to reduce inflammation and alleviate symptoms associated with inflammatory conditions. Its anti-inflammatory properties may contribute to the development of new therapeutic agents for the treatment of various inflammatory diseases.
Used in Anti-cancer Applications:
1H-Benzimidazol-4-amine,6-chloro-(9CI) is used as an anti-cancer agent for its potential to inhibit the growth and proliferation of cancer cells. Its anti-cancer activities may be utilized in the development of novel therapeutic agents for the treatment of various types of cancer.
Used in Medicinal Chemistry Research:
1H-Benzimidazol-4-amine,6-chloro-(9CI) is used as a research compound for its potential role in the development of new pharmaceutical drugs. Its unique chemical structure and pharmacological properties make it a valuable tool for studying the mechanisms of action and potential therapeutic applications in various disease conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 10597-55-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,5,9 and 7 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 10597-55:
(7*1)+(6*0)+(5*5)+(4*9)+(3*7)+(2*5)+(1*5)=104
104 % 10 = 4
So 10597-55-4 is a valid CAS Registry Number.
10597-55-4Relevant academic research and scientific papers
Inhibition of Rat Hepatic Microsomal Aminopyrine N-Demethylase Activity by Benzimidazole Derivatives. Quantitative Structure-Activity Relationships
Murray, Michael,Ryan, Adrian J.,Little, Peter J.
, p. 887 - 892 (2007/10/02)
Eighty-two benzimidazole derivatives have been prepared and tested for the ability to inhibit cytochrome P-450 mediated enzyme activity (aminopyrine N-demethylase) from phenobarbitone-induced rat hepatic microsomes.Using physicochemical parameters and multiple regression analysis, we derived a quantitative structure-activity relationship (QSAR) that describes up to 87percent of the data variance in terms of hydrophobic and electronic effects and the molar refractivity of the substituent in the 2-position of the benzimidazole ring.
