105971-30-0

Basic information

• Product Name: hex-5-enyl-phenyl-amine
• Synonyms: hex-5-enyl-phenyl-amine
• CAS NO: 105971-30-0
• Molecular Weight: 175.274
• Mol File: 105971-30-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: hex-5-enyl-phenyl-amine(CAS DataBase Reference)
• NIST Chemistry Reference: hex-5-enyl-phenyl-amine(105971-30-0)
• EPA Substance Registry System: hex-5-enyl-phenyl-amine(105971-30-0)

Safety Data

• Hazardous Substances Data: 105971-30-0(Hazardous Substances Data)

Upstream product

• 36394-07-7 5-hexenoyl chloride 
• 1577-22-6 5-hexenoic acid 
• 2695-47-8 6-Bromo-1-hexene 
• 62-53-3 aniline 
• 14548-31-3 hex-1-en-5-yne 
• 108-86-1 bromobenzene 
• 34825-70-2 hex-5-en-1-amine 
• 821-41-0 5-Hexen-1-ol 
• 153035-39-3 N-phenylhex-5-enamide 

Downstream Products

• 157099-70-2 N-(hex-5-enyl)-2-iodo-N-phenylbenzamide 
• 1239691-88-3 N-phenyl-2-(p-methoxybenzyl)piperidine 
• 157099-72-4 N-(hex-5-enyl)-2-iodo-N-phenylbenzenesulfonamide 
• 157099-71-3 N-(hex-5-enyl)-N-phenylbenzenesulfonamide 

Relevant articles and documents

Nickel-Catalyzed Aminofluoroalkylation of Alkenes: Access to Difluoroalkylated N-Containing Heterocyclic Compounds

A nickel-catalyzed aminofluoroalkylative cyclization of unactive alkenes with iododifluoromethyl ketones was developed to construct versatile difluoroalkylated Nitrogen-containing heterocycles including aziridines, pyrrolidines and piperidines in moderate to high yields. This method features a broad substrate scope and has been demonstrated on gram scale.

Aerobic intramolecular aminothiocyanation of unactivated alkenes promoted by in situ generated iodine thiocyanate

Aerobic intramolecular aminothiocyanation of unactivated alkenes has been developed by in situ generated iodine thiocyanate under open-flask conditions. This protocol provides a concise and efficient method for synthesizing SCN-containing pyrrolidine, piperidine and indoline derivatives with isolated yields of up to 87%. Furthermore, mixing iodine and sodium thiocyanate with oxygen afforded iodine thiocyanate (ISCN) and dithiocyanatoiodate [I(SCN)2]- which were testified by liquid chromatography mass spectrometry. A mechanistic investigation indicates that iodonium ion and sulfonium ion intermediates might be involved in this transformation.

A bifunctional PdVMgO solid catalyst for the one-pot selective N-monoalkylation of amines with alcohols

It has been found that a bifunctional metal Pd/base (MgO) catalyst performs the selective monoalkylation of amines with alcohols. The reaction goes through a series of consecutive steps in a cascade mode that involves: 1) the abstraction of hydrogen from the alcohol that produces the metal hydride and the carbonyl compound; 2) condensation of the carbonyl with the amine to give an imine, and 3) hydrogenation of the imine with the surface hydrogen atoms from the metal hydride. Based on isotopic and spectroscopic studies and on the rate of each elementary step, a global reaction mechanism has been proposed. The controlling step of the process is the hydride transfer from the metal to the imine. By changing the crystallite size of the Pd, it is demonstrated that this is a structure-sensitive reaction, whereas the competing processes that lead to subproducts are not. On these bases, a highly selective catalyst has been obtained with Pd crystallite size below 2.5 nm in diameter. The high efficiency of the catalytic system has allowed us to extend the process to the one-pot synthesis of piperazines.