106-56-9

Basic information

• Product Name: Morpholine, 2,5-dimethyl-
• Synonyms: 2,5-Dimethylmorpholine; Morpholine, 2,5-dimethyl-
• CAS NO: 106-56-9
• Molecular Formula: C₆H₁₃NO
• Molecular Weight: 115.1735
• Mol File: 106-56-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 150.8°C at 760 mmHg
• Flash Point: 50.1°C
• Appearance: /
• Density: 0.862g/cm³
• Vapor Pressure: 3.78mmHg at 25°C
• Refractive Index: 1.406
• Storage Temp.: 2-8°C
• PKA: 9.07±0.60(Predicted)
• CAS DataBase Reference: Morpholine, 2,5-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Morpholine, 2,5-dimethyl-(106-56-9)
• EPA Substance Registry System: Morpholine, 2,5-dimethyl-(106-56-9)

Safety Data

• Hazardous Substances Data: 106-56-9(Hazardous Substances Data)

Usage

General Description

2,5-dimethylmorpholine is a chemical compound with the molecular formula C6H13NO. It is a heterocyclic amine derivative of morpholine, with two methyl groups attached to the nitrogen atom. It is a clear, colorless liquid with a faint amine-like odor, and it is soluble in water. 2,5-dimethylmorpholine is commonly used as a catalyst in chemical reactions, especially in the production of polyurethane foams, resins, and coatings. It is also used as a pH adjuster, corrosion inhibitor, and in the synthesis of pharmaceuticals and agrochemicals. However, it is important to handle this chemical with care, as it is a skin and eye irritant and may cause respiratory irritation if inhaled.

InChI:InChI=1/C6H13NO/c1-5-4-8-6(2)3-7-5/h5-7H,3-4H2,1-2H3

Upstream product

• 115893-42-0 (β-hydroxy-isopropyl)-(2-hydroxy-propyl)-amine 
• 115206-95-6 (R)-2-Chloro-N-((S)-2-hydroxy-1-methyl-ethyl)-propionamide 
• 115206-95-6 (1'S,2S)-2-Chlor-N-(2'-hydroxy-1'-methylethyl)propionsaeureamid 
• 115206-98-9 (2S,5S)-2,5-Dimethyl-3-oxoperhydro-1,4-oxazin 
• 106-62-7 Dipropylene glycol 

Relevant articles and documents

Steric effects in the catalytic amination of γ-, δ-, and ε-glycols

The amination of butane-1,4-diol, isomeric dipropylene glycols, and cyclohexane-1,4-diyldimethanol in the presence of nickel/copper/chromium catalysts has been studied. The effect of the initial glycol structure on the reaction selectivity has been estima

A concise and efficient synthesis of substituted morpholines

A simple and efficient method has been developed for the synthesis of substituted morpholines by a sequence of coupling, cyclization, and reduction reactions of easily available amino alcohols and α-halo acid chlorides. Various mono-, di-, and trisubstituted morpholines, spiro morpholines, and ring-fused morpholines, as well as morpholine homologues, were synthesized in good to excellent yields by a single methodology under similar reaction conditions. The method was also used in a multigram synthesis of (3S)-3-methylmorpholine.