106012-56-0

Basic information

• Product Name: IMIDAZO[1,2-A]PYRIMIDINE-3-CARBALDEHYDE
• Synonyms: IMIDAZO[1,2-A]PYRIMIDINE-3-CARBALDEHYDE;Imidazo[1,2-a]pyrimidine-3-carboxaldehyde (9CI);Imidazo[1,2-a]pyrimidine-3-carboxaldehyde
• CAS NO: 106012-56-0
• Molecular Formula: C7H5N3O
• Molecular Weight: 147.1341
• Product Categories: ALDEHYDE
• Mol File: 106012-56-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 169-171 °C
• Appearance: /
• Density: 1.39g/cm³
• Refractive Index: 1.695
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 2.85±0.30(Predicted)
• CAS DataBase Reference: IMIDAZO[1,2-A]PYRIMIDINE-3-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: IMIDAZO[1,2-A]PYRIMIDINE-3-CARBALDEHYDE(106012-56-0)
• EPA Substance Registry System: IMIDAZO[1,2-A]PYRIMIDINE-3-CARBALDEHYDE(106012-56-0)

Safety Data

• Hazardous Substances Data: 106012-56-0(Hazardous Substances Data)

Usage

General Description

Imidazo[1,2-a]pyrimidine-3-carbaldehyde is a chemical compound with the molecular formula C9H6N4O. It is a member of the imidazo[1,2-a]pyrimidine family, which are heterocyclic organic compounds that contain both imidazole and pyrimidine rings. Imidazo[1,2-a]pyrimidine-3-carbaldehyde has potential applications in pharmaceutical and agrochemical industries, as it can be used as a building block for the synthesis of various biologically active compounds. Its unique structure and reactivity make it a valuable intermediate in organic chemistry for the production of a wide range of compounds with diverse properties and applications.

InChI:InChI=1/C7H5N3O/c11-5-6-4-9-7-8-2-1-3-10(6)7/h1-5H

Upstream product

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Relevant articles and documents

Microwave-assisted synthesis of 3-formyl substituted imidazo[1,2-a]pyridines

An efficient, metal-free method for the synthesis of 3-formyl imidazo[1,2-a]pyridines is reported. The method utilises commercially available substrates and features a broad substrate scope. The intermediate enamine was isolated and a plausible reaction mechanism proposed.

Pyrrolization processes of vinyl substituted imidazo[1,2-a]pyridine, pyrimidine and 1,8-naphthyridine

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C-3 Hydroxylation of Some Imidazoazines

Reactions of imidazopyridine, pyrimidine and pyrazine (1)-(3) with formaldehyde or acetaldehyde give the corresponding alcohols and secondary products characterized by 1H and 13C n.m.r.X-Ray crystallographic analysis confirms the structure of (6).The two-step sequence of n-butyllithium and reaction with aldehydes with (2)-(3) does not lead to the alcohols but to n-butyl derivatives with substituents at C(7) and C(8) respectively.