106014-87-3 Usage
General Description
3,3-Azetidinedicarboxylic acid, 1-(phenylmethyl)-, also known as 1-phenylmethyl-3,3-azetidine dicarboxylic acid, is a chemical compound with the molecular formula C12H13NO4. It is a non-proteinogenic amino acid and is commonly used as a building block in the synthesis of peptides and pharmaceutical compounds. 3,3-Azetidinedicarboxylic acid, 1-(phenylmethyl)- is known for its ability to inhibit enzymes such as dipeptidyl peptidase IV (DPP-IV), which plays a role in glucose metabolism and is a target for the treatment of type 2 diabetes. Additionally, 3,3-azetidinedicarboxylic acid, 1-(phenylmethyl)- has been studied for its potential applications in the treatment of Alzheimer's disease and cancer. It is important to handle this chemical with care, as it may pose health and environmental risks if not properly managed.
Check Digit Verification of cas no
The CAS Registry Mumber 106014-87-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,6,0,1 and 4 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 106014-87:
(8*1)+(7*0)+(6*6)+(5*0)+(4*1)+(3*4)+(2*8)+(1*7)=83
83 % 10 = 3
So 106014-87-3 is a valid CAS Registry Number.
106014-87-3Relevant articles and documents
PROCESS FOR MAKING AZETIDINE-3-CARBOXYLIC ACID
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Page 26, (2010/02/06)
The present invention is directed to an improved process for synthesizing azetidine-3-carboxylic acid, comprising triflating diethylbis(hydroxymethyl)malonate followed by azetidine ring-formation by intramolecular cyclization using an amine, decarboxylation to give the mono acid azetidine and hydrogenation to give the title compound. Azetidine-3-carboxylic acid is useful as an intermediate for making certain S1P?1#191/Edg1 receptor agonists, which are immunosupressive agents.
