106018-94-4Relevant articles and documents
Synthesis of enantioenriched 1,2-trans-diamines using the borono-Mannich reaction with N-protected α-amino aldehydes
Norsikian, Stéphanie,Beretta, Margaux,Cannillo, Alexandre,Martin, Amélie,Retailleau, Pascal,Beau, Jean-Marie
supporting information, p. 9991 - 9994 (2015/06/22)
The three-component Petasis borono-Mannich reaction starting with easily accessible N-protected α-amino aldehydes produces efficiently and diastereoselectively 1,2-trans-diamines with an enantiomeric excess of up to 98%.