106019-01-6

Upstream product

• 13710-18-4 C₂Cl₃F₃Zn 
• 104-88-1 4-chlorobenzaldehyde 
• 354-58-5 1,1,1-Trichloro-2,2,2-trifluoroethane 

Downstream Products

• 131510-43-5 1-Chloro-4-((E)-2-chloro-1,3,3,3-tetrafluoro-propenyl)-benzene 
• 131510-43-5 1-Chloro-4-((Z)-2-chloro-1,3,3,3-tetrafluoro-propenyl)-benzene 
• 122247-07-8 5-(4-Chloro-phenyl)-3-(2,6-dichloro-phenyl)-4-trifluoromethyl-isoxazole 
• 122247-14-7 4-(4-Chloro-phenyl)-3-(2,6-dichloro-phenyl)-5-trifluoromethyl-isoxazole 
• 122247-00-1 3,5-Bis-(4-chloro-phenyl)-4-trifluoromethyl-isoxazole 
• 122247-11-4 3,4-Bis-(4-chloro-phenyl)-5-trifluoromethyl-isoxazole 
• 82203-84-7 1-(4-chlorophenyl)-3,3,3-trifluoro-1-propyne 
• 118968-66-4 1-[2-chloro-3,3,3-trifluoro-1-propenyl]-4-chlorobenzene 
• 131510-32-2 1-Chloro-4-(2,2-dichloro-1,3,3,3-tetrafluoro-propyl)-benzene 

Relevant academic research and scientific papers

Radical Cyclization of Trifluoromethyl-substituted Carbon: A Facile Preparation of Trifluoromethylated Five-membered Ring Compounds

α-Trifluoromethyl carbon radicals, generated by the tributyltin radical, added intramolecularly to oleginic double bonds to afford the trifluoromethyl-substituted five-membered ring compounds.

A Facile Stereoselcetive Synthesis of (E)-1-Aryl-1,2,3,3,3-pentafluoropropenes and (E)-1-Aryl-2-chloro-1,3,3,3-tetrafluoropropenes

Arenecarbaldehydes ArCHO were allowed to react with a carbenoid reagent CF3CX2Mtl (X=Cl, Mtl=ZnCl, X=F, Mtl=LI) to give the adducts ArCH(OH)CX2CF3 whose hydroxyl group was substituted by fluorine.Dehydrohalogenating of the resultant ArCHFCX2CF3 (X=Cl or F

Efficient Carbonyl Addition of Polyfluorochloroethyl, -ethylidene, and -ethenyl Units by Means of 1,1,1-Trichloro-2,2,2-trifluoroethane and Zinc

Thermally stable zinc carbenoid CF3CCl2ZnCl was prepared from 1,1,1-trichloro-2,2,2-trifluoroethane and zinc powder in N,N-dimethylformamide and was allowed to add to carbonyls of aldehydes and α-keto esters in excellent yields to give 1-substituted 2,2-d

PbBr2/Al-Promoted Reductive Addition of 1,1,1-trichloro-2,2,2-trifluoroethane (Flon) to Aldehydes

Introduction of CF3CCl2 unit into aldehydes with CF3CCl3 has been perfomed successfully by the action of catalytic PbBr2 and Al foils in DMF.

EFFICIENT CARBON-CARBON BOND FORMATION WITH THERMALLY STABLE 1,1-DIHALO-2,2,2-TRIFLUOROETHYLZINC REAGENT

The zinc carbenoids CF3CX2ZnX, prepared from CF3CX3 and zinc powder in dimethylformamide, were found thermally stable to add to aldehyde carbonyls in excellent yields.