106031-53-2Relevant articles and documents
Stereocontrolled Total Synthesis of Lipoxins B
Nicolaou, K. C.,Webber, S. E.
, p. 453 - 461 (2007/10/02)
A stereocontrolled total synthesis of six lipoxin B isomers are described.The flexible and stereoselective strategy involves Sharpless asymmetric epoxidation and pinylborane asymmetric reduction to secure the three hydroxyl-bearing stereocenters and a Wittig-type as well as palladium(0)-copper(I) coupling reactions to construct the carbon skeleton of the target molecules.