106032-61-5

Basic information

• Product Name: D-GLUCOSE-1-D1
• Synonyms: D-GLUCOSE-1-D1;D-[1-2H]GLUCOSE;D-GLUCOSE-1-D;D-glucose-1-D 97 atom % D;dextrose-1-d1;D-Glucose-1-C-d;(3R,4S,5S,6R)-2-deuterio-6-(hydroxymethyl)oxane-2,3,4,5-tetrol
• CAS NO: 106032-61-5
• Molecular Formula: C6H11DO6
• Molecular Weight: 181.16
• Product Categories: 13C & 2H Sugars
• Mol File: 106032-61-5.mol
• Article Data: 6

Chemical Properties

• Melting Point: 150-152 °C(lit.)
• Boiling Point: 410.8 °C at 760 mmHg
• Flash Point: 202.2 °C
• Appearance: /
• Density: 1.741 g/cm³
• Vapor Pressure: 1.83E-08mmHg at 25°C
• Refractive Index: 1.635
• CAS DataBase Reference: D-GLUCOSE-1-D1(CAS DataBase Reference)
• NIST Chemistry Reference: D-GLUCOSE-1-D1(106032-61-5)
• EPA Substance Registry System: D-GLUCOSE-1-D1(106032-61-5)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 106032-61-5(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 106032-61-5 differently. You can refer to the following data:
1. D-[1-2H]glucose, Labelled D-Glucose is a simple sugar that is present in plants. A monosaccharide that may exist in open chain or cyclic conformation if in solution. It plays a vital role in photosynthesis and fuels the energy required for cellular respiration. D-Glucose is used in various metabolic processes including enzymic synthesis of cyclohexyl-α and β-D-glucosides. Can also be used as a diagnostic tool in detection of type 2 diabetes mellitus and potentially Huntington's disease through analysis of blood-glucose in type 1 diabetes mellitus.
2. Labelled D-Glucose is a simple sugar that is present in plants. A monosaccharide that may exist in open chain or cyclic conformation if in solution. It plays a vital role in photosynthesis and fuels the energy required for cellular respiration. D-Glucose is used in various metabolic processes including enzymic synthesis of cyclohexyl-α and β-D-glucosides. Can also be used as a diagnostic tool in detection of type 2 diabetes mellitus and potentially Huntington''s disease through analysis of blood-glucose in type 1 diabetes mellitus.

InChI:InChI=1/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6?/m1/s1/i6D

Upstream product

• 108438-34-2 2,3,4,6-tetra-O-acetyl-D-<1-(2)H>-glucopyranose 
• 2280-44-6 D-Glucose 
• 90-80-2 D-Glucono-1,5-lactone 
• 1334376-67-8 1-α-[1-(2)H]D-glucopyranosyl-α-[1-(2)H]D-glucopyranosyde 

Downstream Products

• 73485-90-2 <1-(2)H>-1,2,3,4,6-penta-O-acetyl-β-D-glucopyranose 

Relevant articles and documents

Synthesis of salacinol-D4 as an internal standard for mass-spectrometric quantitation of salacinol, a potent D-glucosidase inhibitor found in a traditional Ayurvedic medicine “Salacia”

Accurate quantitative analysis of trace principles in extracts of biologically active natural medicines relies on the use of reliable internal standards (ISs), which, in the case of liquid chromatography-mass spectrometry (LC-MS) analysis, commonly corres

Catalytic reaction mechanism based on α-secondary deuterium isotope effects in hydrolysis of trehalose by European honeybee trehalase

Trehalase, an anomer-inverting glycosidase, hydrolyzes only α, α-trehalose in natural substrates to release equimolecular β-glucose and α-glucose. Since the hydrolytic reaction is reversible, α, α-[1, 1′-2H]trehalose is capable of synthesis from [1-2H]glucose through the reverse reaction of trehalase. α-Secondary deuterium kinetic isotope effects (α-SDKIEs) for the hydrolysis of synthesized α, α-[1, 1′-2H]trehalose by honeybee trehalase were measured to examine the catalytic reaction mechanism. Relatively high kH/kD value of 1.53 for α-SDKIEs was observed. The data imply that the catalytic reaction of the trehalase occurs by the oxocarbenium ion intermediate mechanism. In addition, the hydrolytic reaction of glycosidase is discussed from the viewpoint of chemical reactivity for the hydrolysis of acetal in organic chemistry. As to the hydrolytic reaction mechanism of glycosidases, oxocarbenium ion intermediate and nucleophilic displacement mechanisms have been widely recognized, but it is pointed out for the first time that the former mechanism is rational and valid and generally the latter mechanism is unlikely to occur in the hydrolytic reaction of glycosidases.