106058-92-8

Basic information

• Product Name: (R)-Ethyl 4-t-butoxy-3-hydroxybutanoate (R)-α-methoxy-α-trifluoromethylphenylacetic acid ester
• CAS NO: 106058-92-8
• Molecular Weight: 420.426
• Mol File: 106058-92-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-Ethyl 4-t-butoxy-3-hydroxybutanoate (R)-α-methoxy-α-trifluoromethylphenylacetic acid ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-Ethyl 4-t-butoxy-3-hydroxybutanoate (R)-α-methoxy-α-trifluoromethylphenylacetic acid ester(106058-92-8)
• EPA Substance Registry System: (R)-Ethyl 4-t-butoxy-3-hydroxybutanoate (R)-α-methoxy-α-trifluoromethylphenylacetic acid ester(106058-92-8)

Safety Data

• Hazardous Substances Data: 106058-92-8(Hazardous Substances Data)

Upstream product

• 67354-35-2 ethyl 4-(tert-butoxy)-3-oxobutanoate 
• 638-07-3 ethyl (2-chloroaceto)acetate 
• 20445-33-4 (R)-methoxytrifluoromethylphenylacetyl chloride 
• 106058-89-3 ethyl 4-(tert-butoxy)-3-hydroxybutanoate 

Relevant articles and documents

(R)-Ethyl 4-t-Butoxy-3-hydroxybutanoate, a Versatile Chiral Building Block for EPC (Enantiomerically Pure Compound) Syntheses, by Yeast Reduction of Ethyl 4-t-Butoxy-3-oxobutanoate

Reduction of ethyl 4-t-butoxy-3-oxobutanoate with fermenting yeats yields (R)-ethyl 4-t-butoxy-3-hydroxybutanoate in 97percent e.e.Since the protective group is readily removed from the product of reduction, the present procedure provides a simple entry to the "world of chiral blocks" formally derived from (R)-malic acid.