106080-08-4Relevant academic research and scientific papers
Arylcyclobutylmethylamines
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, (2008/06/13)
Compounds of formula I STR1 and pharmaceutically acceptable salts thereof; in which R1 and R2, which are the same or different, are H or an optionally substituted hydrocarbon group or R1 and R2 together with the nitrogen atom to which they are attached form an optionally substituted heterocyclic ring; R3 is an optionally substituted aromatic hydrocarbon group; and R4 is a hydrocarbon group containing at least one substituent selected from the group consisting of hydroxy and acylated derivatives thereof, optionally substituted alkoxy groups, optionally substituted cycloalkyloxy groups, optionally substituted alkylenedioxy groups, oxo and groups of formula S(O)p R5 in which p is 0, 1 or 2 and R5 is an alkyl group, said hydrocarbon group being optionally substituted by additional substituents, are useful in the treatment of depression.
