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5-bromo-2-chloroisonicotinaldehyde is a chemical compound characterized by the molecular formula C6H3BrClNO. It is a derivative of isonicotinaldehyde, featuring both bromine and chlorine substituents on its aromatic ring. 5-bromo-2-chloroisonicotinaldehyde is recognized for its unique structure and properties, which make it a valuable component in various chemical and pharmaceutical applications.

1060802-23-4

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1060802-23-4 Usage

Uses

Used in Organic Synthesis:
5-bromo-2-chloroisonicotinaldehyde is utilized as a building block in organic synthesis for the preparation of a range of biologically active molecules. Its presence of halogenated substituents allows for versatile chemical reactions, making it a key intermediate in the synthesis of complex organic compounds.
Used in Chemical Research:
In the realm of chemical research, 5-bromo-2-chloroisonicotinaldehyde serves as a valuable reagent. Its unique structure facilitates the study of various chemical reactions and mechanisms, contributing to the advancement of chemical knowledge and the development of new synthetic methodologies.
Used in Pharmaceutical Production:
5-bromo-2-chloroisonicotinaldehyde is employed as a reagent in the production of pharmaceuticals. Its ability to be incorporated into the molecular structures of drugs makes it instrumental in the creation of new medicinal compounds with potential therapeutic applications.
Used in Agrochemical Production:
5-bromo-2-chloroisonicotinaldehyde also finds use in the agrochemical industry, where it is used as a reagent in the synthesis of various agrochemicals. Its role in the development of pesticides and other agricultural chemicals is crucial for enhancing crop protection and productivity.
Used in Medicinal Chemistry:
5-bromo-2-chloroisonicotinaldehyde has been studied for its potential applications in medicinal chemistry. Its distinctive structural features and reactivity make it a promising candidate for the design and synthesis of new pharmaceutical agents with improved efficacy and selectivity in treating various diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 1060802-23-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,6,0,8,0 and 2 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1060802-23:
(9*1)+(8*0)+(7*6)+(6*0)+(5*8)+(4*0)+(3*2)+(2*2)+(1*3)=104
104 % 10 = 4
So 1060802-23-4 is a valid CAS Registry Number.
InChI:InChI=1S/C6H3BrClNO/c7-5-2-9-6(8)1-4(5)3-10/h1-3H

1060802-23-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Bromo-2-chloroisonicotinaldehyde

1.2 Other means of identification

Product number -
Other names 5-Bromo-2-chloropyridine-4-carbaldehyde

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1060802-23-4 SDS

1060802-23-4Downstream Products

1060802-23-4Relevant articles and documents

Synthesis of the GPR40 partial agonist MK-8666 through a kinetically controlled dynamic enzymatic ketone reduction

Hyde, Alan M.,Liu, Zhijian,Kosjek, Birgit,Tan, Lushi,Klapars, Artis,Ashley, Eric R.,Zhong, Yong-Li,Alvizo, Oscar,Agard, Nicholas J.,Liu, Guiquan,Gu, Xiuyan,Yasuda, Nobuyoshi,Limanto, John,Huffman, Mark A.,Tschaen, David M.

, p. 5888 - 5891 (2016)

A scalable and efficient synthesis of the GPR40 agonist MK-8666 was developed from a simple pyridine building block. The key step to set the stereochemistry at two centers relied on an enzymatic dynamic kinetic reduction of an unactivated ketone. Directed

HISTONE ACETYLTRANSFERASE (HAT) INHIBITOR AND USE THEREOF

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Paragraph 0669; 0671, (2021/02/25)

The present invention relates to a histone acetyltransferase (HAT) inhibitor. Provided are a compound represented by general formula I, a pharmaceutically acceptable salt, a stereoisomer, an enantiomer, a diastereomer, an atropisomer, a racemate, a polymorph, a solvate or an isotope-labeled compound (including deuterium substitution) thereof, a preparation method therefor, a pharmaceutical composition comprising the same, and use thereof in the treatment of various HAT-related diseases or conditions.

FGFR4 INHIBITOR, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF

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Paragraph 0230-0233, (2019/09/16)

Provided are an FGFR4 inhibitor having the structure of formula (I), and a preparation method therefor and the use thereof. The compound has a very strong inhibitory effect on FGFR4 kinase activity and has a very high selectivity, and can be widely used in the preparation of a drug for treating cancers, especially prostate cancer, liver cancer, pancreatic cancer, esophageal carcinomas, gastric cancer, lung cancer, breast cancer, ovarian carcinomas, colon cancer, skin cancer, glioblastomas or rhabdomyosarcomas, and is expected to be developed into a new generation of FGFR4 inhibitor drugs.

CHROMENOPYRIDINE DERIVATIVES AS PHOSPHATIDYLINOSITOL PHOSPHATE KINASE INHIBITORS

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Paragraph 0422, (2019/07/13)

The invention relates to inhibitors of PI5P4K inhibitors useful in the treatment of cancers, neurodegenerative diseases, inflammatory disorders, and metabolic diseases, having the Formula (I); where A1, A2, G, R1, R2, R3, R4, and W are described herein.

PYRAZOLE DERIVATIVE

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Paragraph 0123; 0124, (2016/03/05)

Provided are a compound expressed by formula (I) or a pharmacologically permissible salt thereof, as well as a drug or drug composition that contains this compound as an active ingredient, having a xanthine oxidase inhibiting effect that is very useful fo

PYRROLO[2,3-C]PYRIDINES AS IMAGING AGENTS FOR NEUROFIBRILARY TANGLES

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Page/Page column 92, (2016/01/01)

Pyrrolopyridine compounds of formula (I) or their pharmaceutically acceptable salts are disclosed, which may be suitable for imaging tau aggregates, b-sheet aggregates, beta-amyloid aggregates or alpha- synuclein aggregates, and hence are useful in binding and imaging tau aggregates in Alzheimer's patients. More specifically, the compounds are used as tracers in positron emission tomography (PET) imaging to study tau deposits in brain in vivo to allow diagnosis of Alzheimer's disease and other neurodegenerative diseases characterized by tau pathology. Futher, the compounds are useful for measuring clinical efficacy of therapeutic agents for Alzheimer's disease and other neurodegenerative diseases characterized by tau pathology.

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