1060815-86-2

Basic information

• Product Name: 2,4-Dichloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidine
• Synonyms: 2,4-Dichloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidine;2,4-Dichloro-5-Methyl-7H-...
• CAS NO: 1060815-86-2
• Molecular Formula: C₇H₅Cl₂N₃
• Molecular Weight: 202.0407
• EINECS: 1308068-626-2
• Mol File: 1060815-86-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Density: 1.572±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 10.58±0.50(Predicted)
• CAS DataBase Reference: 2,4-Dichloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Dichloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidine(1060815-86-2)
• EPA Substance Registry System: 2,4-Dichloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidine(1060815-86-2)

Safety Data

• Hazardous Substances Data: 1060815-86-2(Hazardous Substances Data)

Usage

General Description

2,4-Dichloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidine is a chemical compound with the molecular formula C7H5Cl2N3. It is a synthetic heterocyclic compound that is used in the pharmaceutical industry for various biological and medicinal applications. 2,4-Dichloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidine has been studied for its potential as an anticancer agent and has shown promising results in inhibiting the growth of certain cancer cells. It is also used in the development of novel drug candidates and has the potential for use in the treatment of various diseases. Its unique structure and properties make it a valuable compound for further research and development in the field of medicine and pharmaceuticals.

InChI:InChI=1S/C7H5Cl2N3/c1-3-2-10-6-4(3)5(8)11-7(9)12-6/h2H,1H3,(H,10,11,12)

Upstream product

• 90213-66-4 2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine 
• 900789-14-2 5-bromo-2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine 
• 74-88-4 methyl iodide 
• 67856-03-5 5-methyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diol 

Downstream Products

• 1116240-03-9 2,4-dichloro-5-methyl-7-tosyl-pyrrolo[2,3-d]pyrimidine 
• 1190399-88-2 C₃₁H₄₀N₆O₃S 
• 1190400-75-9 C₃₂H₄₂N₆O₃S 
• 1239876-18-6 2-(3-(2-Chloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)acetonitrile 

Relevant articles and documents

Synthesis and evaluation of FAK inhibitors with a 5-fluoro-7H-pyrrolo[2,3-d]pyrimidine scaffold as anti-hepatocellular carcinoma agents

Focal adhesion kinase (FAK) is a ubiquitous intracellular non-receptor tyrosine kinase, which is involved in multiple cellular functions, including cell adhesion, migration, invasion, survival, and angiogenesis. In this study, a series of 7H-pyrrolo[2,3-d

PROTEIN KINASE INHIBITORS

Compounds, particularly compounds having spleen tyrosine kinase (Syk) inhibition activity, having the following structure: or a pharmaceutically acceptable salt thereof, wherein R1 is structure (a), (b), (c) or (d): and Ra, Rb, Rc, R2, R3, R4, R5, R6 and R7 are as defined herein. Methods associated with preparation and use of the same, as well as pharmaceutical compositions containing the same, are also disclosed, as well as uses of the same to treat a condition or disorder mediated by a Syk and/or JAK kinase.