1060816-11-6 Usage
General Description
2-Bromo-4-methyl-oxazole is a chemical compound with the molecular formula C5H5BrNO. It is a heterocyclic compound, specifically a derivative of oxazole. This chemical has a bromine atom at the 2-position and a methyl group at the 4-position of the oxazole ring. It is commonly used in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. 2-Bromo-4-methyl-oxazole has various applications in the field of medicinal chemistry and drug discovery, and it is considered as an important building block for the synthesis of bioactive molecules. Due to its versatile reactivity, this compound is widely employed in organic synthesis as a valuable intermediate for the preparation of various functionalized oxazole derivatives.
Check Digit Verification of cas no
The CAS Registry Mumber 1060816-11-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,6,0,8,1 and 6 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1060816-11:
(9*1)+(8*0)+(7*6)+(6*0)+(5*8)+(4*1)+(3*6)+(2*1)+(1*1)=116
116 % 10 = 6
So 1060816-11-6 is a valid CAS Registry Number.
InChI:InChI=1S/C4H4BrNO/c1-3-2-7-4(5)6-3/h2H,1H3
1060816-11-6Relevant articles and documents
Widely Exploited, Yet Unreported: Regiocontrolled Synthesis and the Suzuki–Miyaura Reactions of Bromooxazole Building Blocks
Solomin, Vitalii V.,Radchenko, Dmytro S.,Slobodyanyuk, Evgeniy Y.,Geraschenko, Oleksandr V.,Vashchenko, Bohdan V.,Grygorenko, Oleksandr O.
, p. 2884 - 2898 (2019/03/07)
An approach to synthesis of 2-, 4-, and 5-bromooxazoles is described. The method was optimized, and its scope was extended to all three isomeric parents, as well as various alkyl- and aryl-substituted bromooxazoles. It was found that direct regiocontrolled lithiation followed by reaction with electrophilic bromine source was common for all substrates and led exclusively to the target substituted 2-, 4- and 5-bromooxazoles on multigram scale. The utility of the multipurpose building blocks obtained in this work was demonstrated in the Suzuki–Miyaura cross-coupling reaction under parallel synthesis conditions.
