1061266-06-5Relevant articles and documents
Rhodium-catalyzed ring-opening reactions of N-Boc-azabenzonor-bornadiene with chiral amine nucleophiles derived from amino acids
Cho, Yong-Hwan,Tseng, Nai-Wen,Senboku, Hisanori,Lautens, Mark
experimental part, p. 2467 - 2475 (2009/04/05)
The rhodium-catalyzed ring-opening of azabenzonor-bornadienes with chiral amino nucleophiles derived from amino acids such as (S)-proline and (R)-phenylglycine is reported. The desired products were obtained as a mixture of diastereomers, which could be easily separated in high yield. Enantiomerically pure ring-fused nitrogen heterocycles and 1,2-diamines were also obtained by further transformation of the ring-opened products. Georg Thieme Verlag Stuttgart.