1061317-31-4

Basic information

• Product Name: 2-(7-iodo-2,3-dihydrobenzo[b][1,4]dioxin-6-ylthio)-1-(4-methoxybenzyl)-1H-imidazo[4,5-c]pyridin-4-amine
• Synonyms: 2-(7-iodo-2,3-dihydrobenzo[b][1,4]dioxin-6-ylthio)-1-(4-methoxybenzyl)-1H-imidazo[4,5-c]pyridin-4-amine
• CAS NO: 1061317-31-4
• Molecular Weight: 546.388
• Mol File: 1061317-31-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(7-iodo-2,3-dihydrobenzo[b][1,4]dioxin-6-ylthio)-1-(4-methoxybenzyl)-1H-imidazo[4,5-c]pyridin-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(7-iodo-2,3-dihydrobenzo[b][1,4]dioxin-6-ylthio)-1-(4-methoxybenzyl)-1H-imidazo[4,5-c]pyridin-4-amine(1061317-31-4)
• EPA Substance Registry System: 2-(7-iodo-2,3-dihydrobenzo[b][1,4]dioxin-6-ylthio)-1-(4-methoxybenzyl)-1H-imidazo[4,5-c]pyridin-4-amine(1061317-31-4)

Safety Data

• Hazardous Substances Data: 1061317-31-4(Hazardous Substances Data)

Upstream product

• 57744-67-9 6-iodo-1,4-benzodioxane 
• 1012059-50-5 4-amino-1-(4-methoxybenzyl)-1H-imidazo[4,5-c]pyridine-2(3H)-thione 
• 155303-91-6 6,7-diiodo-2,3-dihydrobenzo[b][1,4]dioxine 
• 1012059-49-2 4-chloro-1-(4-methoxybenzyl)-1H-imidazo[4,5-c]pyridine-2(3H)-thione 
• 881844-10-6 2-chloro-N⁴-(4-methoxybenzyl)pyridine-3,4-diamine 
• 2393-23-9 4-methoxy-benzylamine 
• 5975-12-2 2,4-dichloro-3-nitro-pyridine 
• 881844-09-3 2-chloro-N-(4-methoxybenzyl)-3-nitropyridin-4-amine 
• 34302-69-7 2,9-dimethyl-1,10-phenanthroline monohydrate 
• 865-48-5 sodium t-butanolate 

Relevant articles and documents

Fused Amino Pyridines for the Treatment of Lung Cancer

The present invention relates to the use of compounds with fused amino pyridine core for the treatment of malignancies associated with brain and lung. The oral administration of compounds of the instant application results in effective brain penetration and provides for non-intrusive treatment of brain and lung tumors.

FUSED AMINO PYRIDINE AS HSP90 INHIBITORS

The present invention relates to HSP90 inhibitors containing fused amino pyridine core that are useful as inhibitors of HSP90 and their use in the treatment of HSP90 related diseases and disorders such as cancer, an autoimmune disease, or a neurodegenerative disease.