1061378-23-1

Basic information

• Product Name: tert-butyl 3-(3-morpholinopropoxy)phenylcarbamate
• Synonyms: tert-butyl 3-(3-morpholinopropoxy)phenylcarbamate
• CAS NO: 1061378-23-1
• Molecular Weight: 336.431
• Mol File: 1061378-23-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-butyl 3-(3-morpholinopropoxy)phenylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 3-(3-morpholinopropoxy)phenylcarbamate(1061378-23-1)
• EPA Substance Registry System: tert-butyl 3-(3-morpholinopropoxy)phenylcarbamate(1061378-23-1)

Safety Data

• Hazardous Substances Data: 1061378-23-1(Hazardous Substances Data)

Upstream product

• 1018895-28-7 methanesulfonic acid 3-morpholin-4-yl-propyl ester 
• 19962-06-2 tert-butyl 3-hydroxyphenylcarbamate 
• 591-27-5 m-Hydroxyaniline 
• 24424-99-5 di-tert-butyl dicarbonate 
• 4441-30-9 3-morpholin-4-ylpropan-1-ol 

Downstream Products

• 925920-62-3 3-[3-(morpholino)propoxy]benzenamine 
• 1061378-28-6 C₁₅H₂₁ClN₂O₃ 
• 1061377-68-1 1-tert-butyl-3-(3-(3-morpholinopropoxy)phenyl)urea 
• 1061377-69-2 3,3-dimethyl-N-(3-(3-morpholinopropoxy)phenyl)butanamide 
• 1061377-28-3 N-(3-(3-morpholinopropoxy)phenyl)-2-(pyridin-3-yl)acetamide 
• 1061377-43-2 N-[4-(3-morpholin-4-yl-propoxy)-phenyl]-2-phenyl-acetamide 
• 1061377-08-9 1-(3-(3-morpholinopropoxy)phenyl)-3-phenylurea 
• 1061377-30-7 1-(3-(3-morpholinopropoxy)phenyl)-3-(pyridin-3-yl)urea 
• 1061377-23-8 2-(4-fluorophenyl)-N-(3-(3-morpholinopropoxy)phenyl)acetamide 
• 1061377-29-4 1-(4-chlorophenyl)-3-(3-(3-morpholinopropoxy)phenyl)urea 
• 1061377-87-4 cyclohexanecarboxylic acid [3-(3-morpholin-4-yl-propoxy)-phenyl]-amide 
• 1061378-42-4 4-nitrophenyl 3-(3-morpholinopropoxy)phenylcarbamate 
• 1061377-44-3 1-(4-chloro-phenyl)-3-[4-(3-morpholin-4-yl-propoxy)-phenyl]-urea 
• 1061377-09-0 1-(4-fluorophenyl)-3-(3-(3-morpholinopropoxy)phenyl)urea 

Relevant articles and documents

Unsymmetrical non-adamantyl N,N′-diaryl urea and amide inhibitors of soluble expoxide hydrolase

Incorporation of an adamantyl group in prototypical soluble expoxide hydrolase (sEH) inhibitors afforded improved enzyme potency. We explored replacement of the adamantyl group in unsymmetrical ureas and amides with substituted aryl rings to identify equipotent and metabolically stable sEH inhibitors. We found that aryl rings, especially those substituted in the para position with a strongly electron withdrawing substituent, afforded enzyme IC50 values comparable to the adamantyl compounds in an ether substituted, unsymmetrical N,N′-diaryl urea or amide scaffold.