106162-84-9Relevant academic research and scientific papers
Synthesis of Functionalized Styrenes via Palladium-Catalyzed Coupling of Aryl Bromides with Vinyl Tin Reagents
McKean, D. R.,Parrinello, G.,Renaldo, A. F.,Stille, J. K.
, p. 422 - 424 (2007/10/02)
Highly functionalized styrene derivatives have been synthesized in a single step by the palladium-catalyzed coupling of aryl bromides with tributylethenylstannane.Aryl bromides substituted with electron-withdrawing groups couple rapidly under the reaction conditions while bromides containing electron-donating substituents require further addition of catalyst for complete conversion. 1,4-Dibromobenzene can be coupled in a highly selective fashion with either 1 or 2 equiv of tin reagent to give 4-bromostyrene or diethenylbenzene, respectively.
