106163-49-9

Basic information

• Product Name: N-<2-(R)-bromo-3-phenylpropionyl>-L-proline
• Synonyms: N-<2-(R)-bromo-3-phenylpropionyl>-L-proline
• CAS NO: 106163-49-9
• Molecular Weight: 312.206
• Mol File: 106163-49-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-<2-(R)-bromo-3-phenylpropionyl>-L-proline(CAS DataBase Reference)
• NIST Chemistry Reference: N-<2-(R)-bromo-3-phenylpropionyl>-L-proline(106163-49-9)
• EPA Substance Registry System: N-<2-(R)-bromo-3-phenylpropionyl>-L-proline(106163-49-9)

Safety Data

• Hazardous Substances Data: 106163-49-9(Hazardous Substances Data)

Upstream product

• 42990-55-6 (S)-(alpha)-bromobenzenepropanoic acid 
• 23356-96-9 (S)-1-Pyrrolidin-2-yl-methanol 

Downstream Products

• 103336-10-3 Boc-ProψPhe-OH 
• 775263-46-2 (S)-3-Phenyl-2-((S)-1-pyrrolidin-2-ylmethoxy)-propionic acid 
• 98314-62-6 (S,E)-1-(2-(hydroxymethyl)pyrrolidin-1-yl)-3-phenylprop-2-en-1-one 
• 106163-50-2 (3S,6S)-2-oxo-3-(phenylmethyl)-1-aza-4-oxabicyclo<4.3.0>nonane 

Relevant articles and documents

A Method for the Preparation of Stereochemically Defined ψ Pseudodipeptides

A short, stereochemically defined synthesis of (2S,5S)-ψ pseudodipeptides (7a,7b,10) using commercially available, chiral amino acids has been developed.The key step of the synthesis is the intramolecular SN2 displacement of bromine with alkoxide to give 1,4-oxazin-2-ones (6a,6b,9) that are subsequently hydrolyzed to the desired ψ pseudodipeptides.