106174-48-5Relevant academic research and scientific papers
Synthesis of some C-8-modified 3-deoxy-beta-D-manno-2-octulosonic acid analogs as inhibitors of CMP-Kdo synthetase.
Tadanier,Lee,Whittern,Wideburg
, p. 185 - 207 (2007/10/02)
Selective C-8 modifications of 2,6-anhydro-3-deoxy-D-glycero-D-talo-octonic acid ("2,3-dideoxy-beta-D-manno-2-octulosonic acid", 1a) were effected via the protected 8-hydroxy derivatives 2d and 2e. Swern oxidation of 2d and 2e gave the aldehydes 3a and 3b
Synthesis of 8-Substituted Derivatives of the 2-Deoxy Analogue of 3-Deoxy-β-D-manno-2-octulopyranosonic Acid (2-Deoxy-β-KDO) as Inhibitors of 3-Deoxy-D-manno-octulosonate Cytidylyltransferase
Pring, Brian G.,Jansson, Anita M.,Persson, Kerstin,Andersson, Inger,Gagner-Milchert, Ingalill,et al.
, p. 1069 - 1074 (2007/10/02)
The 2-deoxy analogue of 3-deoxy-β-D-manno-2-octulopyranosonic acid (2-deoxy-β-KDO, 2) is a potent inhibitor of the enzyme 3-deoxy-D-manno-octulosonate cytidylyltransferase, which is involved in the biosynthesis of lipopolysaccharide, an essential componen
New 8-substituted derivatives of an anhydrooctonic acid, methods for their preparation, pharmaceutical preparations containing these and intermediates
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, (2008/06/13)
Novel compounds of the formula wherein Y is hydrogen, halogen, amino, acylamino, acyloxy, azido, mercapto, thiocarboxy, the groups in which AA is an amino acid or peptide and W is OH or the same as AA; or physiologically acceptable salts thereof, processe
