106180-60-3Relevant academic research and scientific papers
Antiparasitic Agents: Part VI-Synthesis of 7-Chloro-4-(4-substituted-phenylamino)- and 7-Chloro-4-(4-substituted-piperazin-1-yl)quinolines as Potential Antiparasitic Agents
Agrawal, Vijai K.,Sharma, Satyavan
, p. 550 - 555 (2007/10/02)
The synthesis of a series of 7-chloro-4-(4-hydroxy-3-substituted-phenylamino)quinolines (9-13, 31-40, 58) and 7-chloro-4-(4-substituted-piperazin-1-yl)quinolines (41-51, 53-55) has been carried out.These compounds have been tested for their antimalarial,
THERMALLY INITIATED REACTIONS OF (Z)-EPOXYHEXENYNES A FACILE PREPARATION OF 3,4-ANNULATED FURANS
Eberbach, Wolfgang,Roser, Joachim
, p. 2221 - 2234 (2007/10/02)
An efficient and general access to 3,4-annulated 2-vinylfurans (type II) is provided by the thermally induced ring transformation of epoxyhexenynes (I).Depending on the substitution pattern the reactions proceed either by heating in solution (5a-h) or under short-time thermolysis conditions (6i, j).The results are consistent with a multistep mechanism involving 1-oxacyclohepta-3,4,6-trienes as central intermediates.
