106183-57-7

Upstream product

• 34371-14-7 (5R)-4-hydroxymethyltetrahydrofuran-2-one 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 106183-54-4 tert-butyl (4R)-4,5-O-isopropylidene-3,4,5-trihydroxypentanoate 

Downstream Products

• 176246-90-5 (4S,5R)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-4-(tert-butyl-diphenyl-silanyloxy)-dihydro-furan-2-one 
• 549505-13-7 Methanesulfonic acid (1R,6S,7S)-6-benzyloxy-9-(tert-butyl-diphenyl-silanyloxy)-1-[(R)-2-(4-methoxy-benzyloxy)-1-triethylsilanyloxy-ethyl]-7-methylsulfanylmethoxy-non-3-ynyl ester 
• 549505-02-4 (2R,3R,8S,9S)-8-Benzyloxy-11-(tert-butyl-diphenyl-silanyloxy)-1-(4-methoxy-benzyloxy)-9-methylsulfanylmethoxy-2-triethylsilanyloxy-undec-5-yn-3-ol 
• 549505-14-8 Methanesulfonic acid (1R,6S,7S)-6-benzyloxy-9-(tert-butyl-diphenyl-silanyloxy)-1-[(R)-1-hydroxy-2-(4-methoxy-benzyloxy)-ethyl]-7-methylsulfanylmethoxy-non-3-ynyl ester 
• 549505-03-5 {(3S,4S)-4-Benzyloxy-8-[(2S,3R)-3-(4-methoxy-benzyloxymethyl)-oxiranyl]-3-methylsulfanylmethoxy-oct-6-ynyloxy}-tert-butyl-diphenyl-silane 
• 549505-12-6 (3S,4S)-4-Benzyloxy-1-(tert-butyl-diphenyl-silanyloxy)-8-[(2S,3R)-3-(4-methoxy-benzyloxymethyl)-oxiranyl]-oct-6-yn-3-ol 
• 549504-95-2 (Z)-(3S,4S)-4-Benzyloxy-1-(tert-butyl-diphenyl-silanyloxy)-8-[(2S,3R)-3-(4-methoxy-benzyloxymethyl)-oxiranyl]-oct-6-en-3-ol 

Relevant academic research and scientific papers

EFFICIENT SYNTHESIS OF (S)-5-HYDROXYMETHYL-5(H)-FURAN-2-ONE FROM D-MANNITOL

Chiral synthons - (S)-5-hydroxymethyl-5(H)-furan-2-one and its t-butyldimethylsilyl ether - were synthsized from D-mannitol in 6-7 steps via 2-desoxy-D-ribonolactone derivatives.

A NEW SYNTHESIS OF (S)-5-HYDROXYMETHYL-2(5H)-FURANONE - A MULTIPURPOSE SYNTHON

The multipurpose chiral synthons (S)-5-hydroxymethyl-2(5H)-furanone and its tert-butyldimethylsilyl ether were synthesized from 2,3-O-isopropylidene-D-glyceraldehyde in four or five stages through derivatives of 2-deoxy-D-ribonolactone.