106189-01-9Relevant articles and documents
SYNTHESIS OF A PROTECTED MONODEHYDRO Leu-ENKEPHALIN AND ITS HYDROGENATION CATALYZED BY CHIRAL RHODIUM COMPLEXES
Nuzillard, J. M.,Poulin, J. C.,Kagan, H. B.
, p. 2993 - 2996 (2007/10/02)
(S,S)-Z-(O)Ts-Tyr-Gly2-ΔPhe-Leu-OMe was synthesized.Some chiral rhodium complexes catalyze the reduction of the C=C bond.The stereochemistry of reduction of the ΔPhe moiety was investigated. 93 percent de could be achieved with dipamp as ligand in the cat