1062204-68-5

Basic information

• Product Name: (3-{6-morpholin-4-yl-9-[1-(4-pyridin-4-ylbenzyl)piperidin-4-yl]-9H-purin-2-yl}phenyl)methanol
• Synonyms: (3-{6-morpholin-4-yl-9-[1-(4-pyridin-4-ylbenzyl)piperidin-4-yl]-9H-purin-2-yl}phenyl)methanol
• CAS NO: 1062204-68-5
• Molecular Weight: 561.687
• Mol File: 1062204-68-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (3-{6-morpholin-4-yl-9-[1-(4-pyridin-4-ylbenzyl)piperidin-4-yl]-9H-purin-2-yl}phenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (3-{6-morpholin-4-yl-9-[1-(4-pyridin-4-ylbenzyl)piperidin-4-yl]-9H-purin-2-yl}phenyl)methanol(1062204-68-5)
• EPA Substance Registry System: (3-{6-morpholin-4-yl-9-[1-(4-pyridin-4-ylbenzyl)piperidin-4-yl]-9H-purin-2-yl}phenyl)methanol(1062204-68-5)

Safety Data

• Hazardous Substances Data: 1062204-68-5(Hazardous Substances Data)

Upstream product

• 1062204-25-4 [3-(6-morpholin-4-yl-9-piperidin-4-yl-9H-purin-2-yl)phenyl]methanol 
• 99163-12-9 4-(pyridin-4-yl)benzaldehyde 

Relevant articles and documents

Novel imidazolopyrimidines as dual PI3-Kinase/mTOR inhibitors

This article describes the syntheses and SAR of a series of imidazolopyrimidine derivatives, which are evaluated as inhibitors of PI3-Kinase (PI3 K) and mTOR. These compounds were found to be ATP competitive with good tumor cell growth inhibition, and suppression of pathway specific biomakers such as phosphorylation of Akt at T308.