1062214-10-1

Basic information

• Product Name: N-(3,4-bis(hydroxymethyl)phenyl)-4'-fluorobiphenyl-4-sulfonamide
• Synonyms: N-(3,4-bis(hydroxymethyl)phenyl)-4'-fluorobiphenyl-4-sulfonamide
• CAS NO: 1062214-10-1
• Molecular Weight: 387.432
• Mol File: 1062214-10-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(3,4-bis(hydroxymethyl)phenyl)-4'-fluorobiphenyl-4-sulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3,4-bis(hydroxymethyl)phenyl)-4'-fluorobiphenyl-4-sulfonamide(1062214-10-1)
• EPA Substance Registry System: N-(3,4-bis(hydroxymethyl)phenyl)-4'-fluorobiphenyl-4-sulfonamide(1062214-10-1)

Safety Data

• Hazardous Substances Data: 1062214-10-1(Hazardous Substances Data)

Upstream product

• 22572-84-5 diethyl 4-aminophthalate 
• 5434-21-9 4-aminophthalic acid 
• 1062213-68-6 diethyl 4-(4’-fluorobiphenyl-4-ylsulfonamido)phthalate 
• 1062214-41-8 diethyl-4-(4-bromophenylsulfonamido)phthalate 

Relevant articles and documents

Development of triarylsulfonamides as novel anti-inflammatory agents

Triaylsulfonamides were identified as novel anti-inflammatory agents, acting by inhibition of RANKL and TNFα signaling. Structure-activity studies led to the identification of compounds with in vitro potencies of 50 >50 μM). A representative compound (4k, ABD455) was able to completely prevent inflammation in vivo in a prevention model and was highly effective at controlling inflammation in a treatment model.