1062609-86-2

Basic information

• Product Name: 2,4,6-trifluorophenylsulfur chlorotetrafluoride
• Synonyms: 2,4,6-trifluorophenylsulfur chlorotetrafluoride
• CAS NO: 1062609-86-2
• Molecular Weight: 274.59
• Mol File: 1062609-86-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,4,6-trifluorophenylsulfur chlorotetrafluoride(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-trifluorophenylsulfur chlorotetrafluoride(1062609-86-2)
• EPA Substance Registry System: 2,4,6-trifluorophenylsulfur chlorotetrafluoride(1062609-86-2)

Safety Data

• Hazardous Substances Data: 1062609-86-2(Hazardous Substances Data)

Upstream product

• 476438-29-6 bis(2,4,6-trifluorophenyl) disulfide 
• 372-38-3 1,3,5-trifluorobenzene 

Downstream Products

• 1062610-12-1 2,4,6-trifluorophenylsulfur pentafluoride 
• 1062610-15-4 3-chloro-2,4,6-trifluorophenylsulfur pentafluoride 

Relevant articles and documents

Discovery of practical production processes for arylsulfur pentafluorides and their higher homologues, bis- and tris(sulfur pentafluorides): Beginning of a new era of "super-trifluoromethyl" arene chemistry and its industry

Various arylsulfur pentafluorides, ArSF5, have long been desired in both academic and industrial areas, and ArSF5 compounds have attracted considerable interest in many areas such as medicines, agrochemicals, and other new materials, since the highly stable SF5 group is considered a "super-trifluoromethyl group" due to its significantly higher electronegativity and lipophilicity. This article describes the first practical method for the production of various arylsulfur pentafluorides and their higher homologues, bis- and tris(sulfur pentafluorides), from the corresponding diaryl disulfides or aryl thiols. The method consists of two steps: (Step 1) treatment of a diaryl disulfide or an aryl thiol with chlorine in the presence of an alkali metal fluoride, and (step 2) treatment of the resulting arylsulfur chlorotetrafluoride with a fluoride source, such as ZnF2, HF, and Sb(III/V) fluorides. The intermediate arylsulfur chlorotetrafluorides were isolated by distillation or recrystallization and characterized. The aspects of these new reactions are revealed and reaction mechanisms are discussed. As the method offers considerable improvement over previous methods in cost, yield, practicality, applicability, and large-scale production, the new processes described here can be employed as the first practical methods for the economical production of various arylsulfur pentafluorides and their higher homologues, which could then open up a new era of "super-trifluoromethyl" arene chemistry and its applications in many areas.

PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES

Novel processes for preparing arylsulfur pentafluorides are disclosed. Processes include reacting at least one aryl sulfur compound with a halogen and a fluoro salt to form an arylsulfur halotetrafluoride. The arylsulfur halotetrafluoride is reacted with a fluoride source to form a target arylsulfur pentafluoride.