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CAS

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4-(2,4-Difluorobenzoyl)-piperidine hydrochloride is an organic compound that serves as an intermediate in the synthesis of various pharmaceuticals, particularly antipsychotic medications. It is characterized by its off-white to pale beige solid appearance and plays a crucial role in the development of new drugs for the treatment of mental health disorders.

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  • 106266-04-0 Structure
  • Basic information

    1. Product Name: 4-(2,4-Difluorobenzoyl)-piperidine hydrochloride
    2. Synonyms: (2,4-DIFLUORO-PHENYL)-PIPERIDIN-4-YL-METHANONE HYDROCHLORIDE;4'-(PIPERIDINE)-2,4-DIFLUOROPHENYL ACETOPHONE HYDROCHLORIDE;4-(2,4-DIFLUOROBENZOYL)PIPERIDINE HCL;4-(2,4-DIFLUOROBENZOYL)PIPERIDINE HYDROCHLORIDE;4-(2,4-DIFLUOROBENZOYL)-PYRIDINE HCL;(2,4-DIFLUOROPHENYL)-(4-PIPERIDINYL)METHANONE OXIME HCl;INTERMEDIATES FOR RISPERIDONE;4-(2,4-difluorobenzoyl)-piperidine
    3. CAS NO:106266-04-0
    4. Molecular Formula: C12H14ClF2NO
    5. Molecular Weight: 261.7
    6. EINECS: 1806241-263-5
    7. Product Categories: (intermediate of risperidone);Pharmaceutical;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Intermediates;Building Blocks;C12;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks;New Products for Chemical Synthesis;Piperidines
    8. Mol File: 106266-04-0.mol
  • Chemical Properties

    1. Melting Point: 203-206°C (dec.)
    2. Boiling Point: 350.3 °C at 760 mmHg
    3. Flash Point: 165.7 °C
    4. Appearance: White or light brown powder
    5. Density: N/A
    6. Vapor Pressure: 3.12E-05mmHg at 25°C
    7. Refractive Index: N/A
    8. Storage Temp.: Refrigerator
    9. Solubility: Methanol, Water
    10. Sensitive: Hygroscopic
    11. CAS DataBase Reference: 4-(2,4-Difluorobenzoyl)-piperidine hydrochloride(CAS DataBase Reference)
    12. NIST Chemistry Reference: 4-(2,4-Difluorobenzoyl)-piperidine hydrochloride(106266-04-0)
    13. EPA Substance Registry System: 4-(2,4-Difluorobenzoyl)-piperidine hydrochloride(106266-04-0)
  • Safety Data

    1. Hazard Codes: Xn
    2. Statements: 22-36/37/38
    3. Safety Statements: 26-37
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 106266-04-0(Hazardous Substances Data)

106266-04-0 Usage

Uses

Used in Pharmaceutical Industry:
4-(2,4-Difluorobenzoyl)-piperidine hydrochloride is used as a risperidone intermediate for the synthesis of antipsychotic drugs. It contributes to the development of medications that help manage symptoms of mental health disorders such as schizophrenia and bipolar disorder.
Used in the Synthesis of Benzisoxazole and Benzisothiazole Derivatives:
In the pharmaceutical industry, 4-(2,4-Difluorobenzoyl)-piperidine hydrochloride is also utilized in the preparation of 1,2-benzisoxazole-3-yl and 1,2-benzisothiazol-3-yl derivatives. These derivatives are known for their antipsychotic properties and are essential in the development of new drugs to treat mental health conditions more effectively.

Check Digit Verification of cas no

The CAS Registry Mumber 106266-04-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,6,2,6 and 6 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 106266-04:
(8*1)+(7*0)+(6*6)+(5*2)+(4*6)+(3*6)+(2*0)+(1*4)=100
100 % 10 = 0
So 106266-04-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H13F2NO.ClH/c13-9-1-2-10(11(14)7-9)12(16)8-3-5-15-6-4-8;/h1-2,7-8,15H,3-6H2;1H

106266-04-0 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
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  • Alfa Aesar

  • (H26926)  4-(2,4-Difluorobenzoyl)piperidine hydrochloride, 98%   

  • 106266-04-0

  • 1g

  • 787.0CNY

  • Detail
  • Alfa Aesar

  • (H26926)  4-(2,4-Difluorobenzoyl)piperidine hydrochloride, 98%   

  • 106266-04-0

  • 5g

  • 2421.0CNY

  • Detail
  • Aldrich

  • (L510475)  4-(2,4-Difluorobenzoyl)piperidine hydrochloride  AldrichCPR

  • 106266-04-0

  • L510475-1G

  • 128.70CNY

  • Detail

106266-04-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(2,4-Difluorobenzoyl)-piperidine hydrochloride

1.2 Other means of identification

Product number -
Other names (2,4-difluorophenyl)-piperidin-4-ylmethanone,hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:106266-04-0 SDS

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