106310-21-8

Basic information

• Product Name: 2-(4-TRIFLUOROMETHYLTHIOBENZOXY)-5-NITROTOLUENE
• Synonyms: 2-(4-TRIFLUOROMETHYLTHIOBENZOXY)-5-NITROTOLUENE;3-methyl-4- (4-Trifluoromethylthiobenzoxy)-Nitrobenzene;2-(4-Trifluoromethylthiophenoxy)-5-nitrotoluene;2-(2-Methyl-4-nitrophenoxy)-4-(trifluoroMethyl)benzene-1-thiol
• CAS NO: 106310-21-8
• Molecular Formula: C15H12F3NO3S
• Molecular Weight: 343.32
• Mol File: 106310-21-8.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 393.551 °C at 760 mmHg
• Flash Point: 191.813 °C
• Appearance: /
• Density: 1.396 g/cm³
• Refractive Index: 1.577
• CAS DataBase Reference: 2-(4-TRIFLUOROMETHYLTHIOBENZOXY)-5-NITROTOLUENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-TRIFLUOROMETHYLTHIOBENZOXY)-5-NITROTOLUENE(106310-21-8)
• EPA Substance Registry System: 2-(4-TRIFLUOROMETHYLTHIOBENZOXY)-5-NITROTOLUENE(106310-21-8)

Safety Data

• Hazardous Substances Data: 106310-21-8(Hazardous Substances Data)

Usage

General Description

2-(4-Trifluoromethylthiobenzoxy)-5-nitrotoluene is an organic compound with the molecular formula C14H10F3NO4S. It is a yellow crystalline powder and is used as a building block for the synthesis of various chemical compounds. This chemical is known for its strong odor and is commonly used in the manufacturing of dyes, pharmaceuticals, and agrochemicals. It is important to handle this chemical with caution and follow safety protocols, as it is classified as a hazardous substance with potential health hazards.

InChI:InChI=1/C15H12F3NO3S/c1-10-8-12(19(20)21)4-7-14(10)22-9-11-2-5-13(6-3-11)23-15(16,17)18/h2-8H,9H2,1H3

Upstream product

• 13290-74-9 1-chloro-2-methyl-4-nitrobenzene 
• 825-83-2 4-trifluoromethylbenzenethiol 
• 108-95-2 phenol 
• 171349-95-4 2-methyl-4-nitro-1-phenoxybenzene 
• 461-84-7 (4-trifluoromethylthio)phenol 
• 1413732-47-4 (2,2'-bipyride-kN₁,kN₁')(1,1,1-trifluoromethanethiolato-kS)-copper 
• 30483-75-1 4-bromophenyl-morpholine 
• 1333415-77-2 4-(4-((trifluoromethyl)thio)phenyl)morpholine 
• 811-68-7 silver(I) trifluoromethanethiolate 

Relevant articles and documents

Development of Multigram Scale Synthesis of Trifluoromethylthiolating Reagent: (bpy)CuSCF3

A practical and reproducible procedure for the efficient preparation of (bpy)CuSCF3 (1), a copper reagent for trifluoromethylthiolation reaction, is reported. All reaction parameters were optimized, and reagent 1 was synthesized in 26 g scale.

Preparation method of 3-methyl-4-(4-trifluoromethylthio)benzoxy-nitrobenzene

The invention discloses a preparation method of 3-methyl-4-(4-trifluoromethylthio)benzoxy-nitrobenzene. 4-(trifluoromethylthio)phenol and 3-methyl-4-chloro-nitrobenzene are taken as starting materialsand dissolved in an organic solvent, condensation reaction is performed under the action of a catalyst, water is added for crystallization, and a product is obtained. The method is simple and convenient to operate, has high molar conversion rate and low production cost and is suitable for industrial production, and pollution control is greatly improved.

Method for synthesizing nitrobenzene ether from 2-amino-5-nitrotoluene

The invention relates to the technical field of pharmaceutical synthesis and particularly relates to a method for synthesizing nitrobenzene ether from 2-amino-5-nitrotoluene. The method comprises thefollowing steps: reacting by virtue of 2-amino-5-nitroto