106314-85-6

Basic information

• Product Name: 2-hydroxypropanoic acid - 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine (1:1)
• CAS NO: 106314-85-6
• Molecular Formula: C₁₂H₁₄ClN₅O₃S
• Molecular Weight: 343.7893
• Mol File: 106314-85-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 391.2°C at 760 mmHg
• Flash Point: 190.4°C
• Vapor Pressure: 2.51E-06mmHg at 25°C
• CAS DataBase Reference: 2-hydroxypropanoic acid - 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine (1:1)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxypropanoic acid - 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine (1:1)(106314-85-6)
• EPA Substance Registry System: 2-hydroxypropanoic acid - 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine (1:1)(106314-85-6)

Safety Data

• Hazardous Substances Data: 106314-85-6(Hazardous Substances Data)

Upstream product

• 849585-22-4 LACTIC ACID 
• 30536-19-7 4-amino-5-chloro-2,1,3-benzothiadiazole 
• 61076-80-0 N-acetyl-2-ethylthio-2-imidazoline 

Downstream Products

• 64461-82-1 tizanidine hydrochloride 

Relevant articles and documents

Preparation method of novel central skeletal muscle relaxant

The invention discloses a preparation method of a novel central skeletal muscle relaxant, and particularly relates to a preparation method of tizanidine hydrochloride. The method includes the following steps that firstly, organic acid A, a compound S1 and a compound S2 serve as raw materials react in an organic solvent X to remove a solvent, and a tizanidine organic acid salt S3 crude product is obtained; secondly, the crude product obtained in the first step is added into organic acid A and an organic solvent Y and dissolved at 50-120 DEG C; thirdly, the temperature is reduced by 50-75 DEG C,heat preservation and crystallization are kept for 2-10 hours, then the temperature is cooled again by 10-30 DEG C, heat preservation is conducted, crystallization continues for 3-10 hours, and tizanidine organic acid salt S3 is obtained; fourthly, the tizanidine organic acid salt S3 obtained in the third step serves as the raw material to prepare tizanidine hydrochloride. According to the method, the yield and purity are high, and the method is easy to operate, high in production efficiency, environmentally friendly, safe and suitable for industrial mass production and has wide market application prospects. The molecular formula is as shown in the description.