106314-87-8

Basic information

• Product Name: N-{2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}-L-leucyl-L-phenylalaninamide
• Synonyms: U 27391
• CAS NO: 106314-87-8
• Molecular Formula: C₂₃H₃₆N₄O₅
• Molecular Weight: 448.5557
• Mol File: 106314-87-8.mol
• Article Data: 1

Chemical Properties

• Density: 1.156g/cm³
• Refractive Index: 1.536
• CAS DataBase Reference: N-{2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}-L-leucyl-L-phenylalaninamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-{2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}-L-leucyl-L-phenylalaninamide(106314-87-8)
• EPA Substance Registry System: N-{2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}-L-leucyl-L-phenylalaninamide(106314-87-8)

Safety Data

• Hazardous Substances Data: 106314-87-8(Hazardous Substances Data)

Relevant articles and documents

Hydroxamic acids

The invention provides a series of novel hydroxamic acids of the formula I which are useful as inhibitors of metalloproteases such as endopeptidases and wherein R1 is a hydrophobic group, R2 and R3 are each an amino acid residue, n is 1 or 2, and A is a group of the formula:-, -CHR4.CO.NH2, in which R4 is an amino acid residue. Also described are processes for the manufacture of the hydroxamic acids, pharmaceutically acceptable salts derived from the said acids and pharmaceutical compositions containing a said acid or salt.