106315-28-0

Basic information

• Product Name: 1,25-dihydroxy-21-nor-20-oxavitamin D3
• Synonyms: 1,25-dihydroxy-21-nor-20-oxavitamin D3
• CAS NO: 106315-28-0
• Molecular Formula: C₂₅H₄₀O₄
• Molecular Weight: 404.5827
• Mol File: 106315-28-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 567°Cat760mmHg
• Flash Point: 296.7°C
• Appearance: /
• Density: 1.1g/cm³
• Vapor Pressure: 3.24E-15mmHg at 25°C
• Refractive Index: 1.553
• CAS DataBase Reference: 1,25-dihydroxy-21-nor-20-oxavitamin D3(CAS DataBase Reference)
• NIST Chemistry Reference: 1,25-dihydroxy-21-nor-20-oxavitamin D3(106315-28-0)
• EPA Substance Registry System: 1,25-dihydroxy-21-nor-20-oxavitamin D3(106315-28-0)

Safety Data

• Hazardous Substances Data: 106315-28-0(Hazardous Substances Data)

Usage

General Description

1,25-dihydroxy-21-nor-20-oxavitamin D3 is a synthetic derivative of vitamin D3. It is a potent and selective agonist for the vitamin D receptor, and it has been used in research to study the effects of activating this receptor. This chemical compound has been investigated for its potential therapeutic applications in various medical conditions, including bone disorders, autoimmune diseases, and cancer. It has been shown to have similar effects to the natural hormone 1,25-dihydroxyvitamin D3, which regulates calcium and phosphorus levels in the body, but with potentially reduced side effects. Studies have also suggested that 1,25-dihydroxy-21-nor-20-oxavitamin D3 may have anti-inflammatory and immunomodulatory properties, making it a promising candidate for future drug development.

InChI:InChI=1/C25H40O4/c1-17-19(15-20(26)16-22(17)27)9-8-18-7-5-13-25(4)21(18)10-11-23(25)29-14-6-12-24(2,3)28/h8-9,20-23,26-28H,1,5-7,10-16H2,2-4H3/b18-8+,19-9+/t20-,21+,22+,23?,25+/m1/s1

Upstream product

• 106351-06-8 C₃₇H₄₉N₃O₈ 
• 106351-02-4 C₃₆H₅₈O₇ 
• 106351-05-7 Acetic acid (1S,3R,8S,9S,10R,13S,14S,17S)-3-acetoxy-17-(4-hydroxy-4-methyl-pentyloxy)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-1-yl ester 
• 81089-21-6 [1α,3β]-1,3-bis[(tetrahydro-2H-pyran-2-yl)oxy]androst-5-en-17-one 
• 106351-01-3 (1S,3R,8S,9S,10R,13S,14S,17S)-10,13-Dimethyl-1,3-bis-(tetrahydro-pyran-2-yloxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ol 
• 106351-07-9 (1S,3R,9S,10R,13S,14S,17S)-17-(4-Hydroxy-4-methyl-pentyloxy)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-1,3-diol 
• 106351-04-6 (1S,3R,8S,9S,10R,13S,14S,17S)-17-(4-Hydroxy-4-methyl-pentyloxy)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-1,3-diol 
• 106351-03-5 5-((1S,3R,8S,9S,10R,13S,14S,17S)-1,3-Dihydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yloxy)-pentan-2-one 
• 20998-18-9 1α,3β-dihydroxy-androst-5-en-17-one 
• 53-43-0 dehydroepiandrosterone 

Relevant articles and documents

Synthetic studies of vitamin D analogues. VII. Synthesis of 20-oxa-21-norvitamin D3 analogues

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