106334-26-3

Basic information

• Product Name: 2-(2-Bromopropyl)-1,3-dioxolane
• Synonyms: 2-(2-Bromopropyl)-1,3-dioxolane
• CAS NO: 106334-26-3
• Molecular Formula: C6H11BrO2
• Molecular Weight: 195.05434
• Mol File: 106334-26-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(2-Bromopropyl)-1,3-dioxolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Bromopropyl)-1,3-dioxolane(106334-26-3)
• EPA Substance Registry System: 2-(2-Bromopropyl)-1,3-dioxolane(106334-26-3)

Safety Data

• Hazardous Substances Data: 106334-26-3(Hazardous Substances Data)

Usage

General Description

2-(2-Bromopropyl)-1,3-dioxolane is a chemical compound with the molecular formula C6H11BrO2. It is a clear, colorless liquid that is commonly used as an intermediate in the synthesis of pharmaceuticals and organic compounds. This chemical has a variety of industrial applications, including as a solvent, reagent, and intermediate in organic synthesis. It is also used in the production of agricultural chemicals, dyes, and fragrances. 2-(2-Bromopropyl)-1,3-dioxolane is classified as a hazardous substance and should be handled with care, as it is flammable and may cause irritation to the skin, eyes, and respiratory system upon exposure.

Upstream product

• 107-21-1 ethylene glycol 
• 123-73-9 crotonaldehyde 
• 123-73-9 trans-Crotonaldehyde 

Downstream Products

• 106334-27-4 2-(2-nitropropyl)-1,3-dioxolane 

Relevant articles and documents

Preparation and properties of a novel solution of hydrogen bromide (HBr) in 1,4-dioxane: An alternative reagent to HBr gas without protic solvents

A solution of hydrogen bromide (HBr) in 1,4-dioxane was prepared and investigated for its ability to brominate alcohols, and hydrobrominate alkenes. This study revealed that the brominating ability of this HBr/1,4-dioxane solution is equal or superior to that of hydrobromic acid or HBr in acetic acid. The solution of HBr in 1,4-dioxane is robust, exhibiting no decomposition of the solvent, and retaining 97% of its original concentration, when kept at ?25 °C for 30 days. This solution is a liquid alternative to HBr gas without protic solvents.

UNSYMMETRICAL CONNECTIVE OLEFINATION BY KORNBLUM NITRO-SYNTHESIS : APPLICATIONS IN PHYTUBERIN CHEMISTRY

Kornblum unsymmetrical olefin synthesis employing radical-anion chain crossed-coupling (light catalysed) of a mono- and a gem-di-nitro-compound, followed by reductive NO2 removal, is examined in the context of a hindered olefin structure required for phytuberin synthesis.Whilst successful for a tetrasubstituted olefin model (for which a Witting approach failed), increasing substitution on the β-position of the mono-nitro component supressed the coupling reaction, presumably for steric reasons.An alternative coupling involving a bromonitrocyclohexane and a mononitroacetal caused symmetrical coupling of the mononitro-component in high yield, rather than a crossed reaction.Reductive elimination (using Na2S/DMF) from either rac.- or meso- 1,2-dinitro-1,2-diphenylethane leads to (E)-stilbene 98percent (E) > probably through a stabilised radical or anion.A convenient preparation of triphenylisoxazoline-N-oxide is reported.