106347-74-4Relevant academic research and scientific papers
Synthese de quelques structures encombrees derivees de l'adamantane et de ses analogues par alkylation des ether d'enol trimethylsilyliques
Dubois, Jacques-Emile,Lebbar, Kadija,Lion, Claude,Dugast, Jean-Yves
, p. 905 - 910 (2007/10/02)
Alkylation of trimethylsilyl enol ethers of 2,4-dimethyl-3-pentanone, cyclopentanone and cyclohexanone has been extended to alkylating agents with a cage structure (substituted or functionalized adamantyl, diamantyl, homoadamantyl and noradamantyl chlorides or bromides).This method affords some new cage structured aliphatic and alicyclic ketones.In some cases one observes a new TiCl4 promoted reaction where the bromine in the alkylating agent is replaced by chlorine.This work is a generalization of our previous extended studies on α-alkylation of ketones with tertiary alkylating agents.
