106350-12-3

Upstream product

• 106350-08-7 2-cyclohexyl-2,3,5,6-tetrahydro-4-hydroxyimino-3,5-dioxo-1,2,6-thiadiazine 1,1-dioxide, sodium salt monohydrate 
• 106350-04-3 2-Cyclohexyl-1,1-dioxo-1λ⁶-[1,2,6]thiadiazinane-3,5-dione 
• 122172-62-7 3,4-Diamino-2-cyclohexyl-1,1-dioxo-1H-1λ⁶-[1,2,5]thiadiazol-2-ium; chloride 

Downstream Products

• 131844-02-5 2-Cyclohexyl-4-[2-(5-dimethylaminomethyl-furan-2-ylmethylsulfanyl)-ethylamino]-1,1-dioxo-1,2-dihydro-1λ⁶-[1,2,5]thiadiazol-3-one 

Relevant academic research and scientific papers

Reactivity of Cyanogen towards N-Substituted Sulfamides: Synthesis of 1,2,5-Thiadiazole 1,1-Dioxide Derivatives

The acid-catalyzed cycloaddition of N-substituted sulfamides 1a-f with cyanogen affords 2-substituted 4-amino-2,3-dihydro-3-imino-1,2,5-thiadiazole 1,1-dioxides 5a-f which, in turn, could be easily hydrolyzed to give the corresponding 3-oxo derivatives 2a

Ring Contraction of 1,2,6-Thiadiazines to 1,2,5-Thiadiazoles: Synthesis of 2-Substituted 4-Amino-2,3-dihydro-3-oxo-1,2,5-thiadiazole 1,1-Dioxides

Nitrosation of 2-substituted 2,3,5,6-tetrahydro-3,5-dioxo-1,2,6-thiadiazine 1,1-dioxides (2a-d) yielded the corresponding 4-hydroximino derivatives (3a-d), which by mild acid treatment were converted into 2-substituted 4-amino-2,3-dihydro-3-oxo-1,2,5-thia