106351-98-8 Usage
General Description
2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methyl-amino]benzoyl]amino]-4- phosphono-butanoic acid is a chemical compound that belongs to the group of antifolates. It is a folic acid antagonist and is commonly used as an antineoplastic agent. The compound works by inhibiting the enzyme dihydrofolate reductase, which is essential for the synthesis of DNA, RNA, and proteins in cells. This ultimately leads to the disruption of cell division and the suppression of cancer cell growth. Additionally, it has been investigated for its potential use in the treatment of inflammatory and autoimmune diseases, as well as certain types of infections.
Check Digit Verification of cas no
The CAS Registry Mumber 106351-98-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,6,3,5 and 1 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 106351-98:
(8*1)+(7*0)+(6*6)+(5*3)+(4*5)+(3*1)+(2*9)+(1*8)=108
108 % 10 = 8
So 106351-98-8 is a valid CAS Registry Number.
InChI:InChI=1/C19H23N8O6P/c1-27(9-11-8-22-16-14(23-11)15(20)25-19(21)26-16)12-4-2-10(3-5-12)17(28)24-13(18(29)30)6-7-34(31,32)33/h2-5,8,13H,6-7,9H2,1H3,(H,24,28)(H,29,30)(H2,31,32,33)(H4,20,21,22,25,26)
